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Listar por autor "El-Bekay, Rajaa"
Mostrando ítems 1-10 de 10
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Adipogenic Impairment of Adipose Tissue-Derived Mesenchymal Stem Cells in Subjects With Metabolic Syndrome: Possible Protective Role of FGF2
Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Lhamyani, Said; Clemente-Postigo, María Mercedes
; Alcaide Torres, Juan; Bernal-López, María Rosa; El-Bekay, Rajaa; Tinahones-Madueño, Francisco José[et al.] (Endocrine Society, 2017)
Context: The decreased expansion capacity of adipose tissue plays a crucial role in the onset of disorders associated with metabolic syndrome. Objetive: The aim of this study was to examine the state of adipose tissue-derived ... -
Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.
De Diego‑Otero, Yolanda; Romero-Zerbo, Silvana Yanina; El-Bekay, Rajaa; Decara, Juan; Sánchez-Salido, Lourdes; Rodriguez-de-Fonseca, Fernando; Del Arco-Herrera, Ignacio[et al.] (Springer Nature, 2009)
Fragile X syndrome is the most common genetic cause of mental disability. The mechanisms underlying the pathogenesis remain unclear and specific treatments are still under development. Previous studies have proposed an ... -
Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia.
Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Lhamyani, Said; Salas-Millán, Manuel Julián; Gentile, Adriana Mariel; Romero-Zerbo, Silvana Yanina; Zayed, Hatem; Valderrama-Marcos, José Francisco; Tinahones-Madueño, Francisco José; El-Bekay, Rajaa[et al.] (Wiley, 2017)
Adipose tissue‐derived multipotent mesenchymal cells (ASCs) participate in the information ofblood vessels under hypoxic conditions. It is probable that the susceptibility of ASCs to theinfluence of age and ageing‐associated ... -
Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes.
El-Bekay, Rajaa; Coín-Aragüez, Leticia I.; Fernandez-García, Diego; Oliva Olivera, Wilfredo; Bernal-López, María Rosa; Clemente-Postigo, María Mercedes; Delgado-Lista, Javier; Díaz-Ruiz, Alberto; Guzmán-Ruiz, Rocio; Vázquez-Martínez, Rafael; Lhamyani, Said; Roca-Rodríguez, María del Mar; Fernández-Veledo, Sonia; Vendrell, Joan; Malagón, Maria M.; Tinahones-Madueño, Francisco José[et al.] (British Pharmacological Society, 2016-03-18)
Glucagon-like peptide-1 (GLP-1) analogues improve glycaemic control in type 2 diabetic (T2D) patients and cause weight loss in obese subjects by as yet unknown mechanisms. We recently demonstrated that the GLP-1 receptor, ... -
Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.
El-Bekay, Rajaa; Romero-Zerbo, Silvana Yanina; Decara, Juan; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De Diego‑Otero, Yolanda[et al.] (Wiley, 2007)
Fragile X syndrome is the most common form of inherited mental retardation in humans. It originates from the loss of expression ofthe Fragile X mental retardation 1 (FMR1) gene, which results in the absence of the Fragile ... -
Inflammatory gene expression in adipose tissue according to diagnosis of anxiety and mood disorders in obese and non-obese subjects.
Coín-Aragüez, Leticia I.; Pavón, Francisco Javier; Contreras, Alba; Gentile, Adriana Mariel; Lhamyani, Said; De Diego‑Otero, Yolanda; Casado-Martín, Yolanda; Oliva-Olivera, Wilfredo; Olveira-Fuster, Gabriel María; Tinahones-Madueño, Francisco José; Pérez-Costillas, Lucía María; El-Bekay, Rajaa[et al.] (Springer Nature, 2018)
Psychiatric disorders have been widely reported to be associated with systemic inflammation upregulation and adiposity. However, there are no data that link adipose tissue inflammation to these mental disorders. The analysis ... -
miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes.
Gentile, Adriana Mariel; Lhamyani, Said; Coín-Aragüez, Leticia I.; Clemente-Postigo, María Mercedes; Oliva Olivera, Wilfredo; Romero-Zerbo, Silvana Yanina; García Serrano, Sara; García-Escobar, Eva; Zayed, Hatem; Doblado, Esther; Bermúdez Silva, Francisco Javier; Murri, Mora; Tinahones-Madueño, Francisco José; El-Bekay, Rajaa[et al.] (Wiley, 2019)
Objective: This study aimed to analyze the potential association of different microRNA (miRNA) moleculeswith both type 2 diabetes (T2D) and obesity and determine their target genes.Methods: Quantitative PCR was used to ... -
Rich oleocanthal and oleacein extra virgin olive oil and inflammatory and antioxidant status in people with obesity and prediabetes. The APRIL study: A randomised, controlled crossover study
Ruiz-García, Ignacio; Ortiz-Flores, Rodolfo; Badía, Rocío; García-Borrego, Aranzazu; García-Fernández, María Inmaculada; Lara, Estrella; Martín-Montañez, Elisa; García Serrano, Sara; Valdés, Sergio; Gonzalo, Montserrat; Tapia Guerrero, María José; Fernández-García, José Carlos; Sánchez-García, Alicia; Muñoz-Cobos, Francisca; Calderón-Cid, Miguel; El-Bekay, Rajaa; Covas, María-Isabel; Rojo-Martínez, Gemma; Olveira-Fuster, Gabriel María; Romero-Zerbo, Silvana Yanina; Bermúdez Silva, Francisco Javier[et al.] (Elsevier, 2023)
Background: Oleocanthal and oleacein are olive oil phenolic compounds with well known anti inflammatory and anti-oxidant properties. The main evidence, however, is provided by experimental studies. Few human studies have ... -
RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
Gentile, Adriana Mariel; Lhamyani, Said; Coín-Aragüez, Leticia I.; Oliva Olivera, Wilfredo; Zayed, Hatem; Vega-Rioja, Antonio; Monteseirin, Javier; Romero-Zerbo, Silvana Yanina; Tinahones-Madueño, Francisco José; Bermúdez Silva, Francisco Javier; El-Bekay, Rajaa[et al.] (Public Library of Science, 2016)
Real-time or quantitative PCR (qPCR) is a useful technique that requires reliable reference genes for data normalization in gene expression analysis. Adipogenesis is among the biological processes suitable for this technique. ... -
The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice
Bermúdez Silva, Francisco Javier; Romero-Zerbo, Silvana Yanina; Haissaguerre, Magalie; Ruz-Maldonado, Inmaculada; Lhamyani, Said; El-Bekay, Rajaa; Tabarin, Antoine; Marsicano, Giovanni; Cota, Daniela[et al.] (The Company of Biologists, 2016)
The endocannabinoid system (ECS) is an intercellular signalling mechanism that is present in the islets of Langerhans and plays a role in the modulation of insulin secretion and expansion of the β-cell mass. The downstream ...