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Evidence from cyclostomes for complex regionalization of the ancestral vertebrate brain.
Sugahara, Fumiaki; Pascual-Anaya, Juan; Oisi, Yasuhiro; Kuraku, Shigehiro; Aota, Shin-ichi; Adachi, Noritaka; Takagi, Wataru; Hirai, Tamami; Murakami, Yasunori; Kuratani, Shigeru[et al.] (Nature Research, 2016)The vertebrate brain is highly complex, but its evolutionary origin remains elusive. Because of the absence of certain developmental domains generally marked by the expression of regulatory genes, the embryonic brain of ... -
Thyroid and endostyle development in cyclostomes provides new insights into the evolutionary history of vertebrates
Takagi, Wataru; Sugahara, Fumiaki; Higuchi, Shinnosuke; Kusakabe, Rie; Pascual-Anaya, Juan; Sato, Iori; Oisi, Yasuhiro; Ogawa, Nobuhiro; Miyanishi, Hiroshi; Adachi, Noritaka; Hyodo, Susumu; Kuratani, Shigeru[et al.] (BMC, 2022)The endostyle is an epithelial exocrine gland found in non‑vertebrate chordates (amphioxi and tunicates) and the larvae of modern lampreys. It is generally considered to be an evolutionary precursor of the thyroid gland ...