Listar por autor "Dicks, Matthew DJ"

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Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction

Dicks, Matthew DJ; Betancor, Gilberto; Jimenez-Guardeño, Jose Manuel; Pessel-Vivares, Lucie; Apolonia, Luis; Goujon, Caroline; Malim, Michael H.[et al.] (Public Library of Science, 2018)

Human myxovirus resistance 2 (MX2/MXB) is an interferon-induced post-entry inhibitor of human immunodeficiency virus type-1 (HIV-1) infection. While the precise mechanism of viral inhibition remains unclear, MX2 is localized ...
MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation

Betancor, Gilberto; Jimenez-Guardeño, Jose Manuel; Lynham, Steven; Antrobus, Robin; Khan, Hataf; Sobala, Andrew; Dicks, Matthew DJ; Malim, Michael H.[et al.] (Springer Nature, 2021)

The antiviral cytokine interferon activates expression of interferon-stimulated genes to establish an antiviral state. Myxovirus resistance 2 (MX2, also known as MxB) is an interferon-stimulated gene that inhibits the ...