Listar por autor "Apolonia, Luis"

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Immunoproteasome activation enables human TRIM5α restriction of HIV-1

Jiménez-Guardeño, José Manuel; Apolonia, Luis; Betancor, Gilberto; Malim, Michael H. (Springer Nature, 2019)

Type 1 interferon suppresses viral replication by upregulating the expression of interferon-stimulated genes with diverse antiviral properties1. The replication of human immunodeficiency virus type 1 (HIV-1) is naturally ...
Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction

Dicks, Matthew DJ; Betancor, Gilberto; Jimenez-Guardeño, Jose Manuel; Pessel-Vivares, Lucie; Apolonia, Luis; Goujon, Caroline; Malim, Michael H.[et al.] (Public Library of Science, 2018)

Human myxovirus resistance 2 (MX2/MXB) is an interferon-induced post-entry inhibitor of human immunodeficiency virus type-1 (HIV-1) infection. While the precise mechanism of viral inhibition remains unclear, MX2 is localized ...