Listar por autor "Órpez-Zafra, Teresa"
Mostrando ítems 1-3 de 3
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Decreased soluble IFN-β receptor (sIFNAR2) in multiple sclerosis patients: A potential serum diagnostic biomarker
Órpez-Zafra, Teresa; Pavía-Molina, José
; Hurtado-Guerrero, Isaac; Pinto-Medel, Maria Jesús; Rodríguez-Bada, José Luis; Urbaneja, Patricia; Suardíaz García, Margarita; Villar, Luisa M; Comabella, Manuel; Montalban, Xavier; Alvarez-Cermeño, Jose C; Leyva-Fernández, Laura; Fernández-Fernández, Óscar; Oliver-Martos, Begoña[et al.] (SAGE Journals, 2017)
Background: The soluble isoform of the interferon-β (IFN-β) receptor (sIFNAR2) could modulate the activity of both endogenous and systemically administered IFN-β. Previously, we described lower serum sIFNAR2 levels in ... -
Development and validation of an ELISA for quantification of soluble IFN-β receptor: assessment in multiple sclerosis
Órpez-Zafra, Teresa; Pavía-Molina, José; Pinto-Medel, Maria Jesús; Hurtado-Guerrero, Isaac; Rodríguez-Bada, José Luis; Martín-Montañez, Elisa; Fernández Fernández, Óscar; Leyva-Fernández, Laura; Oliver-Martos, Begoña[et al.] (Taylor & Francis, 2015)
Aim: The soluble isoform of the IFN-β receptor (sIFNAR2) can bind IFN-β and modulate its activity, although its role in autoimmune diseases remains unknown. Methods: A recombinant human sIFNAR2 protein was cloned, ... -
Killer-cell immunoglobulin-like receptor expression on lymphocyte subsets in multiple sclerosis patients treated with interferon-β: evaluation as biomarkers for clinical response
García-León, Juan Antonio; López-Gómez, Carlos; Orpez-Zafra, Teresa; Reyes-Garrido, Virginia; Marín Bañasco, Carmen; Oliver-Martos, Begoña; Fernández-Fernández, Óscar; Leyva-Fernández, Laura[et al.] (Springer Link, 2014)
Background: Both the adaptative and the innate immune systems interplay in multiple sclerosis (MS) pathogeny. Killer-cell immunoglobulin-like receptors (KIRs) are key regulators of the immune response, with activating and ...