Listar por autor "Posadas, Sinforiano"
Mostrando ítems 1-6 de 6
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Anticonvulsant-induced Toxic Epidermal Necrolysis: Monitoring the Immunologic Response.
Leyva-Fernández, Laura
; Torres-Jaén, María Josefa; Posadas, Sinforiano Jose; Blanca, Miguel; Besso, Guillermo; O'Valle, Francisco; García del Moral, Raimundo; Santamaría, Luis F; Juárez, Carlos[et al.] (Elsevier BV, 2000)
Background Toxic epidermal necrolysis is a severe reaction with skin involvement induced by different drugs and other agents. The mechanisms implicated in the induction of the reaction are poorly understood. Objective To ... -
Delayed reactions to drugs show levels of perforin, granzyme B, and Fas-L to be related to disease severity.
Posadas, Sinforiano Jose; Padial, Antonia; Torres-Jaén, María Josefa; Mayorga Mayorga, Cristobalina; Leyva-Fernández, Laura; Sánchez, Elena; Álvarez, Javier; Romano, Antonino; Juárez, Carlos; Blanca, Miguel; Sánchez, Elena[et al.] (Elsevier, 2002)
Background Drugs can induce different immunologic reactions; T-cell mediated responses produce the most severe reactions. Although in vitro studies show that T cells recognize drugs or their metabolites and induce an ... -
Expression of the skin-homing receptor in peripheral blood lymphocytes from subjects with nonimmediate cutaneous allergic drug reactions
Blanca, Miguel; Posadas, Sinforiano Jose; Torres-Jaén, María Josefa; Leyva-Fernández, Laura; Mayorga Mayorga, Cristobalina; González, Lourdes; Juárez, Carlos; Fernández, Javier; Santamaría, Luis F[et al.] (Wiley, 2000)
Background: In nonimmediate cutaneous reactions to drugs, the skin is the organ most frequently involved, and T lymphocytes may play a relevant role. T cells related to skin immune responses express the cutaneous ... -
Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents.
Navarro-Lobato, Irene; Masmudi-Martín, Mariam; López-Aranda, Manuel Francisco; López-Téllez, Juan Félix; Delgado, Gloria; Granados-Durán, Pablo; Gaona-Romero, Celia; Carretero-Rey, Marta; Posadas, Sinforiano; Quirós-Ortega, María Elena; Khan, Zafaruddin[et al.] (Wolters Kluwer Medknow, 2023-11-08)
Memory deficit, which is often associated with aging and many psychiatric, neurological, and neurodegenerative diseases, has been a challenging issue for treatment. Up till now, all potential drug candidates have failed ... -
ROLE OF RGS14 PROTEIN IN VISUALMEMORYAND THE REGULATION OF SYNAPTIC PLASTICITY IN PERIRHINAL CORTEX
Masmudi-Martin, Mariam; Posadas, Sinforiano Jose; Navarro-Lobato, Irene; Delgado, Gloria; López-Téllez, Juan Félix; Bashir, Zafar I.; Khan, Zafaruddin[et al.] (2013-10-31)
Though the concept of participation of perirhinal cortex and frontal cortex in the processing of object memory has long been appreciated, but recently our laboratory extended this to area V2 of visual cortex. We found that ... -
Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction
Posadas, Sinforiano Jose; Leyva-Fernández, Laura; Torres-Jaén, María Josefa; Rodríguez-Bada, José Luis; Bravo, Inmaculada; Rosal, Manuel; Fernández, Javier; Juárez, Carlos; Blanca, Miguel[et al.] (Elsevier, 2000-10)
Background: The mechanisms involved in adverse drug reactions with an immunologic basis (ADRIB) can be antibody dependent, mainly IgE or T cell dependent (sensitized T cells). These mechanisms are regulated by a number of ...