Listar por autor "Ortega-Pinazo, Jesús"
Mostrando ítems 1-5 de 5
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Candidate Gene Study of TRAIL and TRAIL Receptors: Association with Response to Interferon Beta Therapy in Multiple Sclerosis Patients
López-Gómez, Carlos; Pino-Ángeles, Almudena; Órpez-Zafra, Teresa; Pinto-Medel, Mª Jesús; Oliver-Martos, Begoña
; Ortega-Pinazo, Jesús; Arnáiz, Carlos; Guijarro-Castro, Cristina; Varadé, Jezabel; Alvarez-Lafuente, Roberto; Urcelay, Elena; Sánchez-Jiménez, Francisca María; Fernández Fernández, Oscar; Leyva-Fernández, Laura[et al.] (Public Library of Sciences, 2013)
TRAIL and TRAIL Receptor genes have been implicated in Multiple Sclerosis pathology as well as in the response to IFN beta therapy. The objective of our study was to evaluate the association of these genes in relation to ... -
Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis.
Rosell-del-Valle, Cristina; Pedraza-Benítez, María del Carmen; Manuel, Iván; Moreno-Rodríguez, Marta; Rodríguez-Puertas, Rafael; Castilla-Ortega, María Estela; Caramés-Tejedor, José María; Gómez-Conde, Ana Isabel; Zambrana-Infantes, Emma; Ortega-Pinazo, Jesús; Serrano-Castro, Pedro Jesús; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Estivill-Torrús, Guillermo[et al.] (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2021-06-06)
Several studies have demonstrated that lysophosphatidic acid (LPA) acts through its LPA receptors in multiple biological and behavioral processes, including adult hippocampal neurogenesis, hippocampal-dependent memory, and ... -
Cross-reactivity of antibodies against interferon beta in multiple sclerosis patients and interference of the JAK-STAT signaling pathway
Hurtado-Guerrero, Isaac; Pinto-Medel, Maria Jesus; Urbaneja, Patricia; Rodríguez-Bada, José Luis; Ortega-Pinazo, Jesús; Serrano-Castro, Pedro Jesús; Fernández-Fernández, Óscar; Leyva-Fernández, Laura; Oliver-Martos, Begoña[et al.] (Nature, 2017)
Interferon beta (IFNβ) therapy has immunogenic properties and induces the development of neutralizing antibodies (NAbs). From the extensive literature focused in the development of NAbs in multiple sclerosis (MS) patients, ... -
TRAIL/TRAIL receptor system and susceptibility to multiple sclerosis
López-Gómez, Carlos; Fernández, Oscar; García-León, Juan Antonio; Pinto-Medel, María Jesús; Oliver-Martos, Begoña; Ortega-Pinazo, Jesús; Suardíaz-García, Margarita; García-Trujillo, Lucía; Guijarro-Castro, Cristina; Benito-León, Julián; Prat, Isidro; Varadé, Jezabel; Alvarez-Lafuente, Roberto; Urcelay, Elena; Leyva-Fernández, Laura[et al.] (Public Library of Science, 2011-07)
The TNF-related apoptosis inducing ligand (TRAIL)/TRAIL receptor system participates in crucial steps in immune cell activation or differentiation. It is able to inhibit proliferation and activation of T cells and to induce ... -
Vascular Endothelial Growth Factor as a Potential Biomarker of Neuroinflammation and Frontal Cognitive Impairment in Patients with Alcohol Use Disorder
Requena-Ocaña, Nerea; Flores-López, María; Papaseit, Esther; García-Marchena, Nuria; Ruiz-Ruiz, Juan Jesús; Ortega-Pinazo, Jesús; Serrano, Antonia; Pavón-Morón, Francisco Javier; Farré, Magí; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando; Araos Gómez, Pedro Fernando[et al.] (IOAP-MPDI, 2022-04-20)
(1) Background: Alcohol Use Disorder (AUD) is associated with functional disruption of several brain structures that may trigger cognitive dysfunction. One of the mechanisms of alcohol-associated cognitive impairment has ...