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Listar por autor "Martínez-Moreno, Francisco Javier"
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A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
Molina-Hernández, Verónica; Ruiz-Campillo, María Teresa; Martínez-Moreno, Francisco Javier; Buffoni, Leandro; Martinez Moreno, Álvaro; Zafra, Rafael; Bautista, María José; Escamilla-Sánchez, Alejandro; Pérez-Caballero, Raúl; Pérez, José[et al.] (MDPI, 2021-09-30)
Fasciolosis is a parasitic disease of livestock causing important economic losses worldwide and it is also a zoonosis. Current therapy relies on the use of anthelmintic drugs, which is no longer sustainable due to the ... -
Comparative dynamics of peritoneal cell immunophenotypes in sheep during the early and late stages of the infection with Fasciola hepatica by flow cytometric analysis
Pérez-Caballero, Raúl; Martínez-Moreno, Francisco Javier; Zafra, Rafael; Molina-Hernández, Verónica; Pacheco Luque, Isabel; Ruiz-Campillo, María Teresa; Escamilla-Sánchez, Alejandro; Pérez, José; Martinez Moreno, Álvaro; Buffoni, Leandro[et al.] (Springer Nature, 2018-12)
Se cree que las poblaciones celulares peritoneales (PCP) desempeñan un papel crucial durante la respuesta inmunitaria temprana en la infección por Fasciola hepatica mientras que los juveniles recién desenquistados (NEJ) ... -
Distribution of Foxp3+ T cells in the liver and hepatic lymph nodes of goats and sheep experimentally infected with fasciola hepatica
Escamilla-Sánchez, Alejandro; Zafra, Rafael; Pérez, José; McNeilly, Tom; Pacheco Luque, Isabel; Buffoni, Leandro; Martínez-Moreno, Francisco Javier; Molina-Hernández, Verónica; Martinez Moreno, Álvaro[et al.] (Elsevier B.V., 2016-10)
Foxp3 regulatory T cells (Tregs) are now considered to play a key role in modulation of immune responses during parasitic helminth infections. Immunomodulation is a key factor in Fasciola hepatica infection; however, the ... -
Pathological, immunological and parasitological study of sheep vaccinated with the recombinant protein 14-3-3z and experimentally infected with Fasciola hepatica
Pérez-Caballero, Raúl; Siles-Lucas, Mar; González-Miguel, Javier; Martínez-Moreno, Francisco Javier; Escamilla-Sánchez, Alejandro; Pérez, José; Martinez Moreno, Álvaro; Buffoni, Leandro[et al.] (Elsevier B.V., 2018-08)
In this study, the immunogenicity and protective capacity of a new recombinant vaccine candidate, the rFh14-3-3z protein was analysed in sheep experimentally challenged with Fasciola hepatica, in terms of fluke burden, ... -
Study of peritoneal macrophage immunophenotype in sheep experimentally infected with Fasciola hepatica
Ruiz-Campillo, María Teresa; Molina-Hernández, Verónica; Pérez, José; Pacheco Luque, Isabel; Pérez-Caballero, Raúl; Escamilla-Sánchez, Alejandro; Martínez-Moreno, Francisco Javier; Martinez Moreno, Álvaro; Zafra, Rafael[et al.] (Elsevier B.V., 2018-06-15)
During Fasciola hepatica infection, the parasite has the capability to modulate the host immune response towards a non-protector Th2 type instead of Th1. This type of immune response is closely related to the alternativ ...