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Optimizing pain intensity assessment in clinical trials: How many ratings are needed to best balance the need for validity and to minimize assessment burden?
Vega de Carranza, Rocío de la; Sakulsriprasert, Prasert; Miró, Jordi; Jensen, Mark P. (Elsevier, 2024-07)Pain intensity is the most commonly used outcome domain in pain clinical trials. To minimize the chances of type II error (ie, concluding that a treatment does not have beneficial effects, when in fact it does), the ...