Listar por autor "Vila, Javier"
Mostrando ítems 1-4 de 4
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Del revés: metaloproteinasa de la matriz extracelular 2 y su función en el nucleolo
(2018-09-19)Las metaloproteinasas de la matriz extracelular (MMPs) son proteínas que tradicionalmente han sido ubicadas en el exterior celular y su función ha sido relacionada con la remodelación de la matriz extracelular en procesos ... -
Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis
García-Vilas, Javier A.; Rodríguez-Quesada, Ana María
; Medina-Torres, Miguel Ángel (Elsevier, 2017-04)
The health benefits of olive oil are attributed to their bioactive compounds, such as hydroxytyrosol. Previously, we demonstrated that hydroxytyrosol inhibits angiogenesis in vitro. The present study aimed to: i) get further ... -
Mandibular movement analysis by means of a kinematic model applied to the design of oral appliances for the treatment of obstructive sleep apnea
García Reyes, Marcos; Cabrera Castillo, Juan A.; Bataller-Torras, Alex; Vila, Javier; Mayoral Sanz, Pedro (Elsevier, 2020-04-30)
Background: Mandibular advancement devices (MADs) are one of the treatment options used for the obstructive sleep apnea syndrome (OSAS). At present, MADs are designed with standard titration systems, without considering ... -
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects
García-Vilas, Javier A.; Pino-Ángeles, Almudena; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (Elsevier, 2017-01)
The natural bioactive compound damnacanthal inhibits several tyrosine kinases. Herein, we show that -in fact- damancanthal is a multi kinase inhibitor. A docking and molecular dynamics simulation approach allows getting ...