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Listar por autor "Del Arco-Herrera, Ignacio"
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Absence of LPA1 signaling results in defective cortical development
Estivill-Torrús, Guillermo; Llebrez Zayas, Pedro; Matas-Rico, Elisa; Rodríguez de Fonseca, Fernando; Chun, Jerold; Santín-Núñez, Luis Javier; Pedraza-Benítez, María del Carmen
; De-Diego-Barbado, Isabel
; Del Arco-Herrera, Ignacio; Fernández-Llebrez, Pedro
[et al.] (Oxford academy, 2008-04)
Lysophosphatidic acid (LPA) is a simple phospholipid with extracellular signaling properties mediated by specific G protein-coupled receptors. At least 2 LPA receptors, LPA(1) and LPA(2), are expressed in the developing ... -
Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.
De Diego‑Otero, Yolanda; Romero-Zerbo, Silvana Yanina; El-Bekay, Rajaa; Decara, Juan; Sánchez-Salido, Lourdes; Rodriguez-de-Fonseca, Fernando; Del Arco-Herrera, Ignacio[et al.] (Springer Nature, 2009)
Fragile X syndrome is the most common genetic cause of mental disability. The mechanisms underlying the pathogenesis remain unclear and specific treatments are still under development. Previous studies have proposed an ... -
Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.
El-Bekay, Rajaa; Romero-Zerbo, Silvana Yanina; Decara, Juan; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De Diego‑Otero, Yolanda[et al.] (Wiley, 2007)
Fragile X syndrome is the most common form of inherited mental retardation in humans. It originates from the loss of expression ofthe Fragile X mental retardation 1 (FMR1) gene, which results in the absence of the Fragile ... -
Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome
Romero-Zerbo, Silvana Yanina; Decara, Juan; El Bekay Rizky, Rajaa; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De-Diego-Otero, María Yolanda[et al.] (Blackwell Munksgaard, 2009)
Fragile X syndrome is the most common form of inherited mentalretardation. It is typically caused by a mutation of the Fragile X mental-retardation 1 (Fmr1) gene. To better understand the role of the Fmr1 geneand its gene ...