Listar por autor "Moreno, Patricia"
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Actividad inmunomoduladora y antiviral del Propil Propano Tiosulfinato, un compuesto derivado de la cebolla, frente a betanodavirus
Moreno, Patricia; Baños-Arjona, Alberto; Alonso-Sánchez, María del Carmen
; García-Rosado, Esther; Béjar-Alvarado, Julia (2022-11)
Los compuestos organosulfurados de las especies del género Allium, como el PropilPropano Tiosulfinato (PTS), se utilizan como aditivos funcionales en alimentación animal por sus propiedades antimicrobianas. Sin embargo, ... -
Antiviral activity of European sea bass ISG15 against betanodavirus infections
Moreno, Patricia; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (2017)
To study the role of the sea bass ISG15 protein against betanodavirus infections, an in vivo transcription analysis has been performed after RGNNV infection and poly I:C inoculation, and the sea bass ISG15 activity has ... -
Capsid amino acids at positions 247 and 270 are involved in the virulence of betanodaviruses to European sea bass.
Moreno, Patricia; Souto, Sandra; Leiva-Rebollo, Rocío; Borrego-García, Juan José; Bandin, Isabel; Alonso-Sánchez, María del Carmen[et al.] (Nature Pubishing Group, 2019-10-01)
The role of the capsid protein (Cp) amino acids 247 and 270 in the virulence of a RGNNV isolate to sea bass (Dicentrarchus labrax) has been evaluated by the generation of recombinant RGNNV viruses harbouring SJNNV-type ... -
Differential antiviral activity of European sea bass interferon-stimulated 15 protein (ISG15) against RGNNV and SJNNV betanodaviruses.
Moreno, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (ScienceDirect, 2018-09-07)
ISG15 is an antiviral protein acting intracellularly, by conjugation to viral or cellular proteins, or extracellularly, as cytokine. In this work, an in vitro system, consisting of E-11 cells over-expressing European sea ... -
Differential immunogene expression profile of European sea bass (Dicentrarchus labrax, L.) in response to highly and low virulent NN
Moreno, Patricia; Gémez-Mata, Juan; García-Rosado, Esther; Béjar-Alvarado, Julia; Labella Vera, Alejandro Manuel; Souto, Sandra; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2020)
European sea bass is highly susceptible to the nervous necrosis virus, RGNNV genotype, whereas natural outbreaks caused by the SJNNV genotype have not been recorded. The onset and severity of an infectious disease depend ... -
Evaluación de la respuesta inmune en doradas tras la administración de una vacuna inactivada frente a betanodavirus
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno, Patricia; Borrego-García, Juan José; García-Rosado, Esther; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
El virus de la necrosis nerviosa (VNN), género Betanodavirus, familia Nodaviridae, es el agente etiológico de la necrosis nerviosa viral, enfermedad que afecta a peces cultivados en todo el mundo. Existen cuatro especies ... -
Extractos del probiótico Shewanella putrefaciens Pdp11 protegen frente a la infección por RGNNV en cultivo celular
Moreno, Patricia; Balebona-Accino, María del Carmen; Moriñigo-Gutiérrez, Miguel Ángel; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia; García-Rosado, Esther[et al.] (2022)
El agente etiológico de la retinopatía y encefalitis viral (VER) es el virus de la necrosis nerviosa (VNN). Aunque esta enfermedad puede causar una elevada mortalidad en numerosas especies de peces, no existen métodos ... -
Factors associated with use of community mental health services by schizophrenia patients using multilevel analysis
Moreno Küstner, Berta; Mayoral, Fermín; Rivas, Fabio; Angona, Pedro; Requena, Javier; García-Herrera, José María; Navas, Desirée; Moreno, Patricia; Serrano, Antoni; Bellón, Juan A[et al.] (2011-10-07)
Background: Persons with schizophrenia and related disorders may be particularly sensitive to a number of determinants of service use, including those related with illness, socio-demographic characteristics and organizational ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes.
Moreno, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)
Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Inhibition of nervous necrosis virus replication by Shewanella putrefaciens Pdp11 extract
Moreno, Patricia; Álvarez-Torres, Daniel; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen; García-Rosado, Esther[et al.] (Elsevier, 2023)
One of the most relevant infectious diseases affecting farmed fish is the viral encephalopathy and retinopathy, caused by the nervous necrosis virus (NNV). The two commercial vaccines available against this virus have been ... -
Nodavirus-host interplay: what we know and what is next.
Moreno, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2024)
Nervous necrosis virus (NNV) is a bisegmented ssRNA virus that is classified into four species: SJNNV, RGNNV, TPNNV and BFNNV. NNV causes viral nervous necrosis, a disease that affects farmed fish worldwide and in the ... -
Papel del inmunogen isg15 de lubina (Dicentrarchus labrax) en las infecciones por betanodavirus
Moreno, Patricia; García-Rosado, Esther; Borrego-García, Juan José; Alonso-Sánchez, María del Carmen (Universidad de Oviedo, 2016)
En peces, al igual que en vertebrados superiores, la respuesta antiviral innata está mediada por el sistema interferón tipo I (IFN I), que actúa mediante la activación de genes denominados isg (interferon-stimulated genes), ... -
RRGNNV capsid protein amino acids 247 and 270 are involved in betanodavirus virulence to European sea bass (Dicentrarchus labrax)
Moreno, Patricia; Souto, Sandra; Leiva-Rebollo, Rocío; García-Rosado, Esther; Borrego-García, Juan José; Bandín Matos, Isabel; Alonso-Sánchez, María del Carmen[et al.] (2019-09-18)
Recombinant RGNNV viruses harbouring SJNNV-type amino acids at positions 247 and/or 270 (Mut247Dl965, Mut270Dl965, Mut247+270Dl965) were generated by reverse genetics. The effect of these modifications on viral replication ... -
Surveillance of Viruses in Wild Fish Populations in Areas around the Gulf of Cadiz (South Atlantic Iberian Peninsula)
(2014-09-19)This report describes a viral epidemiological study of wild fish around the Gulf of Cadiz (southwestern Iberian Peninsula) and is focused on infectious pancreatic necrosis virus (IPNV), viral hemorrhagic septicemia virus ... -
Tetraselmis suecica and Porphyridium cruentum exopolysaccharides show anti-VHSV activity on RTG-2 cells
Parra-Riofrio, Geovanna; Moreno, Patricia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Uribe-Tapia, Eduardo; Abdala-Díaz, Roberto Teófilo; Béjar-Alvarado, Julia[et al.] (Springer, 2023)
The use of functional feed additives is an important approach to both, prevent and fight, viral diseases in aquaculture. In this regard, microalgae-derived products, and, more specifically, microalgal exopolysaccharides ... -
Transcriptional profile and serological studies of the European sea bass immune response against betanodavirus infections
Moreno, Patricia; López-Jimena, Benjamín; Scapigliati, Giuseppe; Buonocuore, Francesco; García-Rosado, Esther; Borrego-García, Juan José; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2019-07-19)
European sea bass is highly affected by outbreaks of viral nervous necrosis disease, provoked by the nervous necrosis virus (NNV). This virus displays a positive-sense RNA genome composed of two segments, RNA1, encoding ...