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A lower duodenal immune response is associated with an increase of insulin resistance in patients with morbid obesity
Ho-Plágaro, Ailec; Saltiago-Fernández, Concepción; García Serrano, Sara; Rodríguez, Cristina; Garrido-Sánchez, Lourdes; Escamilla-Sánchez, Alejandro; Gonzalo, Montserrat; Montiel Casado, Custodia; Alcaín-Martínez, Guillermo; García-Muñoz, Beatriz; Ruiz-Santana, Natalia; Vázquez Pedreño, Luis; García-Fuentes, Eduardo[et al.] (Springer Nature, 2019-09-25)
The intestinal immune response could play an important role in obesity-related comorbidities. We aim to study the profile of duodenal cytokines and chemokines in patients with morbid obesity (MO), its relation with insulin ... -
Adipose tissue as a therapeutic target for vascular damage in Alzheimer's disease
Bettinetti-Luque, Miriam; Trujillo-Estrada, Laura Isabel; García-Fuentes, Eduardo; Andreo-López, Juana; Sánchez-Varo, Raquel María
; Gómez-Mediavilla, Ángela; López, Manuela G.; Gutiérrez, Antonia; Baglietto-Vargas, David; Garrido-Sánchez, Lourdes; García-Caballero, Melissa[et al.] (Wiley, 2023-09-01)
Adipose tissue has recently been recognized as an important endocrine organ that plays a crucial role in energy metabolism and in the immune response in many metabolic tissues. With this regard, emerging evidence indicates ... -
Comparison of the use of desflurane vs. propofol in aortic valve replacement surgery: Differences in nephroprotection: An Explorative and Hypothesis-Generating Study.
Guerrero-Orriach, José Luis; Malo Manso, Alfredo; Nuñez Galo, Mercedes; Bellido-Estévez, Inmaculada
; Ruiz-Salas, Amalio; Cruz Mañas, José; Garrido-Sánchez, Lourdes; González-Álvarez, Laura[et al.] (MDPI, 2022-07-31)
Introduction: The cardioprotective effect of halogenated drugs in cardiac surgery has been the subject of several studies. However, there is scarcity of data on their potential nephroprotective effects. Aortic valve ... -
FABP4 Dynamics in Obesity: Discrepancies in Adipose Tissue and Liver Expression Regarding Circulating Plasma Levels
Queipo-Ortuño, María Isabel; Escoté Miró, Xavier; Ceperuelo-Mallafré, Victoria; Garrido-Sánchez, Lourdes; Miranda, Merce; Clemente-Postigo, María Mercedes
; Pérez-Pérez, Rafael; Peral Fuentes, Belén; Cardona-Díaz, Fernando
; Fernández Real, José M; Tinahones-Madueño, Francisco José
; Vendrell Ortega, Joan[et al.] (PLOS (Public Library of Science), 2012)
Background FABP4 is predominantly expressed in adipose tissue, and its circulating levels are linked with obesity and a poor atherogenic profile. Objective In patients with a wide BMI range, we analyze FABP4 expression ... -
Non‑alcoholic fatty liver disease in patients with morbid obesity: the gut microbiota axis as a potential pathophysiology mechanism
Cornejo Pareja, Isabel María; Mohamed-Reda, Amiar; Ocaña-Wilhelmi, Luis Tomás; Soler Humanes, Rocio; Arranz-Salas, Isabel María
; Garrido-Sánchez, Lourdes; Gutiérrez-Repiso, Carolina; Tinahones-Madueño, Francisco José
[et al.] (Springer Nature, 2024-01-24)
Alterations in gut microbiota are associated with the pathogenesis of metabolic diseases, including metabolic-associated fatty liver disease (MAFLD). The aim of this study was to evaluate gut microbiota composition and ... -
Relación de los niveles de vitamina D y la expresión de VDR en tejido adiposo con el índice de masa corporal y el perfil glucémico.
Clemente-Postigo, María Mercedes; Muñoz-Garach, Araceli; Garrido-Sánchez, Lourdes; Bernal-López, Rosa; Moreno-Santos, Inmaculada; Castellano-Castillo, Daniel; Fernández-García, Diego; Cardona-Díaz, Fernando
; Tinahones-Madueño, Francisco José
; Macías-González, Manuel[et al.] (2012)
Este estudio analizó la relación entre los niveles de vitamina D (25(OH)D3), la expresión del receptor de vitamina D (VDR) en tejido adiposo visceral, el índice de masa corporal (IMC) y el perfil glucémico en 119 sujetos ... -
Serum 25-Hydroxyvitamin D and Adipose Tissue Vitamin D Receptor Gene Expression: Relationship with Obesity and Type 2 Diabetes
Clemente-Postigo, María Mercedes; Muñoz Garach, Araceli; Serrano, Marta; Garrido-Sánchez, Lourdes; Bernal-López, María Rosa; Fernandez-García, Diego; Moreno Santos, Inmaculada; Garriga, Nuria; Castellano-Castillo, Daniel; Camargo, Antonio; Fernández Real, José M; Cardona-Díaz, Fernando
; Tinahones-Madueño, Francisco José
; Macías-González, Manuel[et al.] (Endocrine Society, 2015)
Context: The relationship between 25-hydroxyvitamin D [25(OH)D] and obesity and type 2 diabetes is not completely understood. Vitamin D receptor (VDR) expression in adipose tissue (AT) is related to obesity and might be ... -
Synergic effect of metabolic syndrome and lipodystrophy on oxidative stress and inflammation process in treated HIV-patients.
González-Doménech, Carmen María; Plaza-Andrades, Isaac; Garrido-Sánchez, Lourdes; Queipo-Ortuño, María Isabel
(Elsevier, 2022-06-06)
The aim of this study was to assess the effect of lipodystrophy (LD) associated to metabolic syndrome (MS) on oxidative stress and inflammation in a cohort of 243 HIV-infected patients with MS, all of them under three ... -
The Relationship between Depressive Symptoms, Quality of Life and miRNAs 8 Years after Bariatric Surgery.
Mela, Virginia; Agüera, Zaida; Álvarez Bermúdez, María Dolores; Martín-Reyes, Flores; Granero, Roser; Sánchez-García, Ana; Oliva-Olivera, Wilfredo; Tomé, Monica; Moreno-Ruiz, Francisco Javier; Soler Humanes, Rocio; Fernández-Serrano, José Luis
; Sánchez-Gallegos, María Pilar
; Martínez-Moreno, José Manuel
; Sancho-Marín, Raquel; Fernández-Aranda, Fernando; García-Fuentes, Eduardo; Tinahones-Madueño, Francisco José
; Garrido-Sánchez, Lourdes[et al.] (MDPI, 2023-09-22)
Background: There are conflicting results on whether weight loss after bariatric surgery (BS) might be associated with quality of life (QoL)/depressive symptomatology. We aim to deter- mine whether BS outcomes are associated ...