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Exploring the Antiangiogenic Potential of Solomonamide A Bioactive Precursors: In Vitro and In Vivo Evidences of the Inhibitory Activity of Solo F-OH During Angiogenesis
Carrillo, Paloma; Martínez-Póveda, Beatriz Amparo; Cheng-Sánchez, Iván; Guerra, Jessica; Tobia, Chiara; López-Romero, Juan Manuel
; Sarabia-García, Francisco Ramón
; Medina-Torres, Miguel Ángel
; Rodríguez-Quesada, Ana María
[et al.] (2019-04-15)
Marine sponges are a prolific source of bioactive compounds. In this work, the putative antiangiogenic potential of a series of synthetic precursors of Solomonamide A, a cyclic peptide isolated from a marine sponge, was ... -
Extracellular Matrix-Remodeling Enzymes as Targets for Natural Antiangiogenic Compounds
Carrillo, Paloma; García-Caballero, Melissa; Bernal, Manuel; Manrique-Poyato, María Inmaculada; Martínez-Póveda, Beatriz Amparo
; Rodríguez-Quesada, Ana María
; Medina-Torres, Miguel Ángel
[et al.] (Springer Nature Switzerland, 2022-12)
Angiogenesis, or new blood vessels formation, comprises a series of tight regulated and coordinated steps guided by the balance between proangiogenic and antiangiogenic signals. Although physiological angiogenesis occurs ...