Listar por autor "Morales Loyola, Rodrigo"

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Are amyloids infectious? Prions and prion-like proteins: myths and facts

Morales Loyola, Rodrigo (2018-06-01)

Transmissible Spongiform Encephalopathies (TSEs) or prion diseases are a group of fatal neurodegenerative disorders affecting mammals. Albeit their low incidence in humans, prion diseases are a subject of passionate research ...
Conformational Aβ strains and cross-seeding mechanism in Alzheimer’s disease pathogenesis: In vivo studies in transgenic animal models

Gómez Gutiérrez, Rubén (UMA Editorial, 2022)

Accumulation of amyloid-beta (Aβ) fibrils in the brain is associated with Alzheimer’s disease (AD) pathology. These fibrils exhibit distinct conformations or “strains” as consequence of variations in their molecular ...