Listar por autor "Guerrero Vásquez, Guillermo A."
Mostrando ítems 1-3 de 3
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An olefin cross-metathesis approach to depudecin and stereoisomeric analogues
Cheng-Sánchez, Iván; García-Ruiz, Cristina; Guerrero Vásquez, Guillermo A.; Sarabia-García, Francisco Ramón
(ACS, 2017)
A new total synthesis of the natural product (−)-depudecin, a unique and unexplored histone deacetylase (HDAC) inhibitor, is reported. A key feature of the synthesis is the utilization of an olefin cross-metathesis strategy, ... -
Synthesis and Antitumor Activity Evaluation of Compounds Based on Toluquinol
Cheng-Sánchez, Iván; Torres-Vargas, José Antonio; Martínez-Póveda, Beatriz Amparo; Guerrero Vásquez, Guillermo A.; Medina, Miguel Ángel; Sarabia-García, Francisco Ramón; Quesada, Ana R.[et al.] (MDPI, 2019-08-23)
Encouraged by the promising antitumoral, antiangiogenic, and antilymphangiogenic properties of toluquinol, a set of analogues of this natural product of marine origin was synthesized to explore and evaluate the effects of ... -
Synthesis of New Analogues of the Bengamides: Peptidyl Bengamides and Molecular Probes
Aguera-Suárez, Ana María; Porras Alcalá, Cristina; Guerrero Vásquez, Guillermo A.; Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón (2017-07-20)
Isolated from sponges of the Jaspidae family, first members where discovered in 1986. The bengamides represent an interesting and unprecedented family of natural products that displayed striking antitumor activities [1]. ...