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Listar por autor "Cheung, Alwin"
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Amyloid propagation in a sporadic model of Alzheimer disease
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Huynh, Kelly; Nguyen, Marie; Cheung, Alwin; Tran, Janine; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2021-11-04)Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Amyloid-b seeding and propagation processes in a hAb-KI model of Alzheimer's disease
Trujillo-Estrada, Laura Isabel; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Núñez-Díaz, Cristina; Forner, Stefania; Martini, Alessandra C.; Da Cunha, Celia; Shahnawaz, Mohammad; Soto, Claudio; Moreno-González, Inés; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2020-12-17)Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Human amyloid seeds aggregate more efficient than seeds from old 3xtg-ad mice
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Huynh, Kelly; Thu Nguyen, Marie Minh; Cheung, Alwin; Tran, Janine Pham; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2022)Aims: Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Human and mouse seeds differentially affect AB aggregation by modulating the inflammatory response.
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Morales-Cabello, Mario; Fatuarte Juli, Ivan; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; LaFerla, Frank; Gutiérrez-Pérez, Antonia; Baglietto-Vargas, David[et al.] (2023)Abstract text: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prionlike process. These amyloid aggregation ... -
Human and mouse seeds differentially affect Aβ aggregation by modulating the inflammatory response
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Minh Thu Nguyen, Marie; Cheung, Alwin; Pham Tran, Janine; Da Cunha, Celia; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Cadete-Martini, Alessandra; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2023)Background: Alzheimer’s Disease (AD) is a neurodegenerative proteinopathy in which Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. These amyloid aggregation ... -
The effect of different amyloid seeds and animal hosts on amyloid propagation in Alzheimer's Disease
Andreo-López, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Do Huynh, Kelly; Thu Nguyen, Marie Minh; Cheung, Alwin; Pham Tran, Janine; Trujillo-Estrada, Laura Isabel; Núñez-Díaz, Cristina; Martini, Alessandra C.; Forner, Stefania; Gutiérrez-Pérez, Antonia; LaFerla, Frank; Baglietto-Vargas, David[et al.] (2022-07-13)Abstract text: Alzheimer's Disease is a neurodegenerative proteinopathy in which recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like ...