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Listar por autor "Labella, Marina"
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Advances and highlights in T and B cell responses to drug antigens
Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Fernández-Duarte, Tahía Diana; Céspedes Lagos, José Antonio; Labella, Marina; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-07)The immunological mechanisms involved in drug hypersensitivity reactions (DHRs) are complex, and despite important advances, multiple aspects remain poorly understood. These not fully known aspects are mainly related to ... -
Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes
Bogas, Gador; Ariza, Adriana; Vázquez-Revuelta, Paula; Labella, Marina; Madrigal-Burgaleta, R.; Fernández-Santamaría, Rubén; Calvo-Serrano, Silvia; Villar-Chamorro, Esther; Martín-Clavo, Susana; Lebrón-Martín, Clara; Mayorga, Cristobalina; Doña, Inmaculada; Torres, María J.[et al.] (Wiley, 2024)Background Delabelling pathways offer confirmatory diagnosis and can prevent unnecessary second-line therapies or drug desensitization procedures after chemotherapeutic hypersensitivity reactions (CHT-HSRs). However, these ... -
Detection of Serum-Specific IgE by Fluoro-Enzyme Immunoassay for Diagnosing Type I Hypersensitivity Reactions to Penicillins
Ariza Veguillas, Adriana; Mayorga Mayorga, Cristobalina; Bogas Herrera, Gádor; Gaeta, Francesco; Salas, María; Valluzzi, Rocco Luigi; Labella, Marina; Pérez-Sánchez, Natalia Isabel; Caruso, Cristiano; Molina, Ana; Fernández-Duarte, Tahía Diana; Torres-Jaén, María Josefa; Romano, Antonino[et al.] (IOAP-MPDI, 2022-06-23)Diagnosis of type I hypersensitivity reactions (IgE-mediated reactions) to penicillins is based on clinical history, skin tests (STs), and drug provocation tests (DPTs). Among in vitro complementary tests, the fluoro-enzyme ... -
Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study
Céspedes Lagos, José Antonio; Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Bogas Herrera, Gádor; Doña, Inmaculada; Rondón, Carmen; Salas, María; Labella, Marina; Frecha, Cecilia; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Fernández-Duarte, Tahía Diana[et al.] (Wiley, 2022-12-07)Amoxicillin (AX) combined or not with clavulanic acid (CLV) is frequently involved in IgE-mediated reactions. Drug provocation test (DPT) is considered as the gold standard for diagnosis, although contraindicated in high-risk ... -
LPS in combination with amoxicillin increases BAT sensitivity to amoxicillin IgE‐mediated hypersensitivity
Céspedes Lagos, José Antonio; Fernández-Santamaría, Rubén; Bogas Herrera, Gádor; Ariza Veguillas, Adriana; Doña, Inmaculada; Salas, María; Labella, Marina; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Frecha, Cecilia[et al.] (Wiley, 2024)β-lactams (BLs), and among them, amoxicillin (AX) are the most current prescribed antibiotics to treat bacterial infections,1 and their use is related to an increasing prevalence of drug hypersensitivity reactions (DHRs),2 ... -
Resensitization in suspected penicillin allergy
Doña, Inmaculada; Guidolin, Lucia; Bogas Herrera, Gádor; Olivieri, Elisa; Labella, Marina; Schiapolli, Michele; Saenz de Santa María-García, Rocío; Dama, Annarita; Salas, María; Senna, Gianenrico; Bonadonna, Patrizia; Torres-Jaén, María Josefa[et al.] (Wiley, 2022-09-06)The diagnosis of allergic reactions to penicillins (AR-PEN) is very complex as there is a loss of sensitization over time, which leads to negative skin tests (STs) and specific IgE in serum, and even to tolerance to the ... -
Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions
Fernández-Santamaría, Rubén; Bogas Herrera, Gádor; Montañez-Vega, María Isabel; Ariza Veguillas, Adriana; Salas, María; Céspedes Lagos, José Antonio; Labella, Marina; Paris, Juan Luis; Pérez-Sánchez, Natalia Isabel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina[et al.] (Wiley, 2022-05-24)Background Immediate drug hypersensitivity reactions (IDHRs) to clavulanic acid (CLV) have increased in the last decades due to a higher consumption alongside amoxicillin (AX). Due to its chemical instability, diagnostic ... -
The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine
Labella, Marina; Céspedes Lagos, José Antonio; Doña, Inmaculada; Shamji, Mohamed H.; Agache, Ioana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-24)