Listar por autor "Matilla-Cabello, Gonzalo"
Mostrando ítems 1-5 de 5
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Clinical presentation, causative drugs and outcome of patients with autoimmune features in two prospective DILI registries
García-Cortés, Miren
; Ortega-Alonso, Aida; Matilla-Cabello, Gonzalo; Medina-Cáliz, Inmaculada; Castiella, Agustin; Conde, Isabel; Bonilla-Toyos, Elvira; Pinazo-Bandera, José M.; Hernandez, Nelia; Tagle, Martin; Nunes, Vinicius; Parana, Raymundo; Bessone, Fernando; Kaplowitz, Neil; Lucena-González, María Isabel; Alvarez-Alvarez, Ismael; Robles-Díaz, María Mercedes; Andrade-Bellido, Raúl Jesús[et al.] (Wiley, 2023)
Background & aims: Idiosyncratic drug-induced liver injury (DILI) with autoimmune features is a liver condition with laboratory and histological characteristics similar to those of idiopathic autoimmune hepatitis (AIH), ... -
Control compounds for preclinical drug-induced liver injury assessment: Consensus-driven systematic review by the ProEuroDILI network
(Elsevier, 2024)Background & Aims Idiosyncratic drug-induced liver injury (DILI) is a complex and unpredictable event caused by drugs, and herbal or dietary supplements. Early identification of human hepatotoxicity at preclinical stages ... -
Immunophenotyping to improve the mechanistic understanding of idiosyncratic drug-induced liver injury: clinical implications and future directions
Cueto Sánchez, Alejandro José; Di Zeo-Sánchez, Daniel Enrique; Segovia-Zafra, Antonio; Matilla-Cabello, Gonzalo; Bodoque-García, Ana; Lucena-González, María Isabel; Villanueva-Paz, Marina[et al.] (Open Exploration, 2023-04-26)
The late event onset of a fraction of idiosyncratic drug-induced liver injury (DILI) cases and the link observed by genome-wide association studies (GWASs) of certain human leucocyte antigen (HLA) alleles with DILI due to ... -
Methods for causality assessment of idiosyncratic drug-induced liver injury
The diagnosis of idiosyncratic drug-induced liver injury (DILI) is a challenging task due to the lack of specific features or definitive diagnostic tools. A minimum of clinical and pharmacological information is required, ... -
Modeling drug-induced liver injury: current status and future prospects.
Di Zeo-Sánchez, Daniel Enrique; Segovia-Zafra, Antonio; Matilla-Cabello, Gonzalo; Pinazo-Bandera, José; Andrade-Bellido, Raúl Jesús; Lucena-González, María Isabel; Villanueva-Paz, Marina[et al.] (Taylor & Francis, 2022-09-16)
Introduction Idiosyncratic drug-induced liver injury (iDILI) is a challenging and unpredictable multifactorial condition. At present, validated preclinical models for the prediction of the hepatotoxic potential of a given ...