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Mostrando ítems 1-8 de 8
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A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology
Carbonell-Ballesteros, Max; Durán-Nebreda, Salva; Montañez, Raúl; Macía, Javier; Rodríguez-Caso, Carlos Francisco (Oxfrod University Press, 2014-12-16)Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly ... -
A morphospace for synthetic organs and organoids: the possible and the actual.
Ollé-Vila, Aina; Durán-Nebreda, Salva; Conde-Pueyo, Núria; Montañez, Raúl; Solé, Ricard V. (Oxford University Press, 2016)Efforts in evolutionary developmental biology have shed light on how organs are developed and why evolution has selected some structures instead of others. These advances in the understanding of organogenesis along with ... -
Emergence of proto-organisms from bistable stochastic differentiation and adhesion.
Durán-Nebreda, Salva; Bonforti, Adriano; Montañez, Raúl; Valverde, Sergi; Solé, Ricard V. (The Royal Society, 2016-04-13)The rise of multicellularity in the early evolution of life represents a major challenge for evolutionary biology. Guidance for finding answers has emerged from disparate fields, from phylogenetics to modelling and synthetic ... -
Population dynamics of synthetic terraformation motifs.
Solé, Ricard V.; Montañez, Raúl; Durán-Nebreda, Salva; Rodríguez-Amor, Daniel; Sardanyés, Josep (The Royal Society, 2018-07-04)Ecosystems are complex systems, currently experiencing several threats associated with global warming, intensive exploitation and human-driven habitat degradation. Because of a general presence of multiple stable states, ... -
Spatial dynamics of synthetic microbial mutualists and their parasites.
Rodríguez-Amor, Daniel; Montañez, Raúl; Durán-Nebreda, Salva; Solé, Ricard V. (PLOS, 2017-08-21)A major force contributing to the emergence of novelty in nature is the presence of cooperative interactions, where two or more components of a system act in synergy, sometimes leading to higher-order, emergent phenomena. ... -
Spatial self-organization in hybrid models of multicellular adhesion.
Bonforti, Adriano; Durán-Nebreda, Salva; Montañez, Raúl; Solé, Ricard V. (American Institute of Physics, 2016-10-26)Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different ... -
Synthetic circuit designs for earth terraformation
Solé, Richard; Montañez, Raúl; Durán-Nebreda, Salva (Springer Nature, 2015-07-18)Background: Mounting evidence indicates that our planet might experience runaway effects associated to rising temperatures and ecosystem overexploitation, leading to catastrophic shifts on short time scales. Remediation ... -
Synthetic collective intelligence.
Solé, Ricard V.; Rodríguez-Amor, Daniel; Durán-Nebreda, Salva; Conde-Pueyo, Núria; Carbonell-Ballesteros, Max; Montañez, Raúl[et al.] (Elsevier, 2016)Intelligent systems have emerged in our biosphere in different contexts and achieving different levels of complexity. The requirement of communication in a social context has been in all cases a determinant. The human ...