Listar por autor "Benítez-Martín, Carlos"
Mostrando ítems 1-15 de 15
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A Turn-On Two-Photon Fluorescent Probe for Detecting Lysosomal Hydroxyl Radicals in Living Cells.
Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio
; Pearson, John; Nájera-Albendín, Francisco; Pérez-Pomares, José María; Perez-Inestrosa, Ezequiel[et al.] (Elsevier, 2019)
The detection of reactive oxygen species (ROS) in biological systems and its imaging is of great importance. Among them, the hydroxyl radical (radical dotOH) stands out as one of the most reactive, playing an important ... -
Benzotriazole-based multidonor-acceptor systems as attractive two-photon absorption dye platforms
Benítez-Martín, Carlos; Donoso, Beatriz; Torres-Moya, Ivan; Herrera-Imbroda, Jesús; Díaz-Ortiz, Ángel; Nájera-Albendín, Francisco; Prieto, Pilar; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Elsevier, 2022-02-03)
Pyrazine-decorated benzotriazole cores allow the orthogonal combination of two dipolar systems within a single molecule. A series of this type of derivatives was synthesized and their photophysical features were studied. ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
Benítez-Martín, Carlos; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (2018-11-15)
Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
Nájera-Albendín, Francisco; Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel (Real Sociedad Española de Química, 2018-06-20)
Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ... -
Extended Alkenyl and Alkynyl Benzotriazoles with enhanced Two‐Photon Absorption properties as a promising alternative to Benzothiadiazoles
Torres-Moya, Ivan; Benítez-Martín, Carlos; Donoso, Beatriz; Tardio, Carlos; Martin, Raul; Carrillo, Jose Ramon; Diaz-Ortiz, Angel; Nájera-Albendín, Francisco; Prieto, Pilar; Perez-Inestrosa, Ezequiel[et al.] (Wiley-VCH Verlag GmbH & Co, 2019)
A series of donor–p–acceptor–p–donor (D-p-A-p-D) benzoazole dyes with 2H-benzo[d][1,2,3]triazole or BTDcores have been prepared and their photophysical proper-ties characterized. The properties of these compounds dis-play ... -
Indolenine-Based Derivatives as Customizable Two-Photon Fluorescent Probes for pH Bioimaging in Living Cells
Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pearson, John; Nájera-Albendín, Francisco; Pérez-Pomares, José María; Perez-Inestrosa, Ezequiel[et al.] (American Chemical Society, 2020)
Novel pH probes based on 2-(6-methoxynaphthalen-2-yl)-3,3-dimethyl3H-indole have been synthesized and characterized. These compounds display excellent “off−on” fluorescence responses to acidic pH especially under two-photon ... -
New indolium fluorofores for two-photon absortion (2PA) bioimaging applications
The development of organic materials with 2PA has attracted intensive attention in the past two decades [1]. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section (σ2PA) ... -
New molecules based indolium for two-photon absortion bioimaging applications
Benítez-Martín, Carlos; Pérez-de-Inestrosa-Villatoro, Ezequiel; Nájera-Albendín, Francisco (Universidad de Extremadura, 2017)
The development of organic materials with 2PA has attracted intensive attention in the past two decades. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section and good ... -
Novel probes for simultaneous dual-colour labelling of mitochondria and lysosomes.
Cellular activity depends on the accurately controlled and synchronised functions of the subcellular organelle ensemble. In this context, lysosomes and mitochondria are central to cellular metabolism as major contributors ... -
“Off-on” two-photon indolenine probes for pH bioimaging
Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pearson, John R.; Nájera-Albendín, Francisco; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2019-10-25)
Fluorescence-based biosensors have become an indispensable tool in modern biology. These molecules can be used to monitor processes inside living cells and in real-time. The control of the pH is crucial in multiple biological ... -
Rapid amplitude-modulation of a diarylethene photoswitch: En route to contrast-enhanced fluorescence imaging
(The Royal Society of Chemistry, 2021)A water soluble diarylethene (DAE) derivative that displays exceptionally intense fluorescence from the colorless open form has been synthesized and characterized using UV/vis spectroscopy and fluorescence microscopy. ... -
Synthesis and characterization of new chromophores with two-photon absorption properties and study of their application in bioimaging
(UMA Editorial, 2022-02-02)A consencuencia de la naturaleza no invasiva de la luz, los métodos basados en fluorescencia han adquirido un rol fundamental para la compresión de los procesos biológicos, comprendiendo desde el estudio de procesos celulares ... -
Tailoring two-photon fluorescent probes for pH bioimaging in living cells
Nájera-Albendín, Francisco; Benítez-Martín, Carlos; Guadix-Domínguez, Juan Antonio; Pearson, John R.; Pérez-Pomares, José María; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (2022-06-27)
Fluorescence biosensors are indispensable basic tools in modern biology. These type of molecules allow real-time visualization of biological events inside living cells. Especially important in many of these processes ... -
Toward Two-Photon Absorbing Dyes with Unusually Potentiated Nonlinear Fluorescence Response
Benítez-Martín, Carlos; Li, Shiming; Dominguez-Alfaro, Antonio; Nájera-Albendín, Francisco; Perez-Inestrosa, Ezequiel; Pischel, Uve; Andréasson, Joakim[et al.] (American Chemical Society, 2020)
The combination of two two-photon-induced processes in a Förster resonance energy transfer (FRET)-operatedphotochromic fluorene-dithienylethene dyad lays the foundation for the observation of a quartic dependence of the ... -
Tuning pKa in new molecules based on indolines for two-photon absorption bioimaging applications
Benítez-Martín, Carlos; Nájera-Albendín, Francisco; Pérez-de-Inestrosa-Villatoro, Ezequiel (Real Sociedad Española de Química, 2018-06-20)
Fluorescence-based biosensors have become essential tools for modern biology, allowing real-time monitoring of biological processes within living cells. The differences between pH play a significant role in multiple ...