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Listar por autor "Borroto-Escuela, Dasiel O."
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Evidence for a synergistic effect of NPY1R agonist co-administered with Ketamine in rats: relevance to neurodegenerative and mood disorders.
Moreno Madrid, Isabel; Arrabal-Gómez, José Carlos; Díaz-Sánchez, Estela; Álvarez-Contino, José Erik; Barbancho-Fernández, Miguel Ángel
; Sánchez-Pérez, José Andrés; Blanco-Reina, Encarnación
; Beltrán-Casanueva, Rasiel; Hernández-García, Aracelis; Bayolo-Guanche, Juan Vicente; Romero-Imbroda, Jesús; Fuxe, Kjell; Borroto-Escuela, Dasiel O.; García-Casares, Natalia
; Serrano-Castro, Pedro; Narváez-Peláez, Manuel
[et al.] (2024)
Introduction/Objetives: Major depressive disorder is one of the most prevalent health problems worldwide and its current therapeutic approach still generates great dissatisfaction due to its limited efficacy, unwanted ... -
Existence of FGFR1-5-HT1AR heteroreceptor complexes in hippocampal astrocytes. Putative link to 5-HT and FGF2 modulation of hippocampal gamma oscillations
Narváez-Peláez, Manuel; Andrade-Talavera, Yunieski; Valladolid-Acebes, Ismael; Fredriksson, Magnus; Siegele, Pia; Hernandez-Sosa, Alejandro; Fisahn, André; Fuxe, Kjell; Borroto-Escuela, Dasiel O.[et al.] (Elsevier, 2020-06-15)
The majority of the fibroblast growth factor receptor 1-serotonin 1 A receptor (FGFR1-5-HT1AR) heterocomplexes in the hippocampus appeared to be located mainly in the neuronal networks and a relevant target for antidepressant ... -
Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus
Borroto-Escuela, Dasiel O.; Pita-Rodríguez, Mariana; Fores-Pons, Ramón; Barbancho-Fernández, Miguel Ángel; Fuxe, Kjell; Narváez-Peláez, Manuel
[et al.] (Wiley, 2021-02-21)
A need for new antidepressants is necessary since traditional antidepressants have several flaws. Neuropeptide Y(NPY) Y1 receptor (NPYY1R) and galanin (GAL) receptor 2 (GALR2) interact in several regions of the limbic ... -
GALR2 and Y1R agonists intranasal infusion enhanced adultventral hippocampal neurogenesis and antidepressant‐likeeffects involving BDNF actions
Álvarez-Contino, José Erik; Díaz-Sánchez, Estela; Mirchandani-Duque, Marina; Sánchez-Pérez, José Andrés; Barbancho-Fernández, Miguel Ángel; López-Salas, Alexander; García-Casares, Natalia
; Fuxe, Kjell; Borroto-Escuela, Dasiel O.; Narváez-Peláez, Manuel
[et al.] (Wiley, 2023)
Dysregulation of adult hippocampal neurogenesis is linked to major depressive disorder(MDD), with more than 300 million people diagnosed and worsened by the COVID‐19pandemic. Accumulating evidence for neuropeptideY (NPY) ... -
Neuropeptide Y receptor 1 and galanin receptor 2 (NPY1R-GALR2) interactions in the dentate gyrus and their relevance for neurogenesis and cognition
Beltran-Casanueva, Rasiel; Hernández-García, Aracelis; de Amo García, Paula; Blanco-Reina, Encarnación; Serrano-Castro, Pedro; García-Casares, Natalia
; Fuxe, Kjell; Borroto-Escuela, Dasiel O.; Narváez, Manuel[et al.] (2024-02-14)
Introduction: This study may unveil novel insights into the interactions between neuropeptide Y receptor 1 (NPY1R) and galanin receptor 2 (GALR2), in the dentate gyrus of the dorsal hippocampus, shedding light on their ... -
Synergistic Effects of Intranasally Administered GALR2 and Y1R Agonists on Cognitive and Mood-Related Behaviors in Adult Rats: Implications for Neurodegenerative and Mood Disorders
Moreno Madrid, Isabel; Arrabal-Gómez, José Carlos; Serrano-Castro, Pedro; Díaz-Sánchez, Estela; Álvarez-Contino, José Erik; Barbancho-Fernández, Miguel-Ángel; Sánchez-Pérez, José Andrés; Blanco-Reina, Encarnación
; Fuxe, Kjell; Borroto-Escuela, Dasiel O.; García-Casares, Natalia
; Narváez-Peláez, Manuel
[et al.] (2024-06)
Abstract body: Background: The complexity of neurodegenerative and mood disorders necessitates innovative therapeutic strategies beyond current treatments. This study explores the combined therapeutic potential of Galanin ...