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Listar por autor "González-Mariscal, Isabel"
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Abnormal cannabidiol ameliorates inflammation preserving pancreatic beta cells in mouse models of experimental type 1 diabetes and beta cell damage
González-Mariscal, Isabel; Pozo-Morales, Macarena; Romero-Zerbo, Silvana Yanina
; Espinosa-Jiménez, Vanesa; Escamilla-Sánchez, Alejandro; Sánchez-Salido, Lourdes; Cobo-Vuilleumier, Nadia; Gauthier, Benoit R.; Bermúdez Silva, Francisco Javier[et al.] (Elsevier, 2021-12-03)
The atypical cannabinoid Abn-CBD improves the inflammatory status in preclinical models of several pathologies, including autoimmune diseases. However, its potential for modulating inflammation in autoimmune type 1 diabetes ... -
Efficacy and safety of basal insulin degludec 100 IU/mL versus glargine 300 IU/mL for type 1 diabetes: the single-center INEOX randomized controlled trial.
Ruiz de Adana Navas, María Soledad; Domínguez, Marta Elena; Morillas, Virginia; Colomo, Natalia; Vallejo Mora, María del Rosario; Guerrero, Mercedes; García-Escobar, Eva; Carreira-Soler, Mónica; Romero-Zerbo, Silvana Yanina; Linares, Francisca; González-Mariscal, Isabel; Bermúdez Silva, Francisco Javier; Olveira-Fuster, Gabriel María; Rojo-Martínez, Gemma[et al.] (Elsevier, 2023)
Aims To compare efficacy and safety of degludec 100 IU/mL (Deg-100) and glargine 300 IU/mL (Gla-300) in adults with type 1 diabetes. Methods Open-label, single-center, randomized, parallel-group, 24-week trial in adults ... -
The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease
Romero-Zerbo, Silvana Yanina; García-Fernández, María Inmaculada; Espinosa-Jiménez, Vanesa; Pozo-Morales, Macarena; Escamilla-Sánchez, Alejandro; Sánchez-Salido, Lourdes; Lara, Estrella; Cobo-Vuilleumier, Nadia; Rafacho, Alex; Olveira-Fuster, Gabriel María; Rojo-Martínez, Gemma; Gauthier, Benoit R.; González-Mariscal, Isabel; Bermúdez Silva, Francisco Javier[et al.] (Frontiers, 2020-03-06)
Background and Aims: The synthetic atypical cannabinoid Abn-CBD, a cannabidiol (CBD) derivative, has been recently shown to modulate the immune system in different organs, but its impact in obesity-related meta-inflammation ... -
(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice
González-Mariscal, Isabel; Carmona-Hidalgo, Beatriz; Winkler, Matthias; Unciti-Broceta, Juan D.; Escamilla-Sánchez, Alejandro; Gómez-Cañas, María; Fernández-Ruiz, Javier; Fiebich, Bernd L.; Romero-Zerbo, Silvana Yanina; Bermúdez Silva, Francisco Javier; Collado, Juan A.; Muñoz, Eduardo[et al.] (Elsevier B.V., 2021-07-01)
Natural cannabidiol ((-)-CBD) and its derivatives have increased interest for medicinal applications due to their broad biological activity spectrum, including targeting of the cannabinoid receptors type 1 (CB1R) and type ...