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Listar por autor "Bennett, David LH"
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A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat
Perkins, James R; Antunes-Martins, Ana; Calvo, Margarita; Grist, John; Rust, Werner; Schmid, Ramona; Hildebrandt, Tobias; Kohl, Matthias; Orengo, Christine A.; McMahon, Stephen B; Bennett, David LH[et al.] (SAGE Publications, 2014-01-28)The past decade has seen an abundance of transcriptional profiling studies of preclinical models of persistent pain, predominantly employing microarray technology. In this study we directly compare exon microarrays to ... -
CXCL5 mediates UVB irradiation-induced pain.
Dawes, John M; Calvo, Margarita; Perkins, James Richard; Paterson, Kathryn J; Kiesewetter, Hannes; Hobbs, Carl; Kaan, Timothy K.Y.; Orengo, Christine A.; Bennett, David LH; McMahon, Stephen B[et al.] (AAAS, 2011-07-06)Many persistent pain states (pain lasting for hours, days, or longer) are poorly treated because of the limitations of existing therapies. Analgesics such as nonsteroidal anti-inflammatory drugs and opioids often provide ... -
ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data
Perkins, James Richard; Dawes, John M; McMahon, Steve B; Bennett, David LH; Orengo, Christine A.; Kohl, Matthias[et al.] (BMC, 2012-07)Background: Measuring gene transcription using real-time reverse transcription polymerase chain reaction (RT-qPCR) technology is a mainstay of molecular biology. Technologies now exist to measure the abundance of many ...