Listar por autor "García-Castro, Miguel"
Mostrando ítems 1-7 de 7
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Evidence as conformational molecular switch of 1,4-bis(4-vinylpyridyl)benzene adsorbed on a nanostructured silver surface: A synergetic study of femtosecond transient absorption spectra, electrochemical SERS records and DFT calculations
López-Tocón, Isabel
; García-Castro, Miguel; Otero, Juan Carlos (Elsevier, 2024)
The electrochemical surface-enhanced Raman spectra (SERS) of 1,4-bis(4-vinylpyridyl)benzene (bvpb) recorded at different electrode potentials with three excitation wavelengths (785, 532 and 473 nm) point out there exists ... -
Exploring the reactivity of chiral glycidic amides for their applications in synthesis of bioactive compounds.
Sarabia-García, Francisco Ramón; Vivar García, Carlos; García-Ruiz, Cristina; Sánchez-Ruiz, Antonio; Pino-González, María Soledad; García-Castro, Miguel; Chammaa, Samy[et al.] (Wiley, 2014-05)
A new class of chiral sulfonium salts, derived from L- and D-methionine, has been designed and successfully employed in our laboratories for the diastereoselective synthesis of glycidic amides. The epoxy amides obtained ... -
Green synthesis of silver nanoparticles and its combination with Pyropia columbina (Rhodophyta) extracts for a cosmeceutical application
González-Conde, Mercedes; Vega Sánchez, Julia; López-Figueroa, Félix; García-Castro, Miguel; Moscoso, Ana; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel[et al.] (MDPI, 2023-03-10)
We report the green synthesis of silver nanoparticles (AgNPs) by using daisy petals (Bellis perennis), leek (Allium porrum) and garlic skin (Allium sativum) as reducing agents and water as solvent. AgNPs are obtained with ... -
n-Tuples on Scaffold Diversity Inspired by Drug Hybridisation to Enhance Drugability: Application to Cytarabine
García-Castro, Miguel; Fuentes-Ríos, David; López-Romero, Juan Manuel; Romero, Antonio; Moya-Utrera, Federico; Díaz-Morilla, Amelia; Sarabia-García, Francisco Ramón[et al.] (MDPI, 2023-12-13)
A mathematical concept, n-tuples are originally applied to medicinal chemistry, especially with the creation of scaffold diversity inspired by the hybridisation of different commercial drugs with cytarabine, a synthetic ... -
Nanoscale biocompatible structures generated from fluorinated tripodal phenylenes on gold nanoprisms
García-Castro, Miguel; Moscoso, Ana; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel; Contreras-Cáceres, Rafael; Díaz-Morilla, Amelia[et al.] (Wiley, 2022-03-09)
Modification of gold substrates with a stable, uniform and ultrathin layer of biocompatible materials is of tremendous interest for the development of bio-devices. We present the fabrication of hybrid systems consisting ... -
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria
Porras Alcalá, Cristina; Moya-Utrera, Federico; García-Castro, Miguel; Sánchez-Ruiz, Antonio; López-Romero, Juan Manuel; Pino-González, María Soledad; Díaz-Morilla, Amelia; Kitamura, Seiya; W. Wolan, Dennis; Prados, Jose; Melguizo, Consolación; Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón[et al.] (IOAP-MPDI, 2022-05-31)
The bengamides comprise an interesting family of natural products isolated from sponges belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled with their unique mechanism of action and ... -
Transition metal-free [2,3]-sigmatropic rearrangement in the reaction of sulfur ylides with allenoates
García-Castro, Miguel; Moya-Utrera, Federico; Sarabia-García, Francisco Ramón (RSC, 2023-08)
An unprecedented transition metal free [2,3]-sigmatropic rearrangement involving stabilized sulfur ylides and allenoates has been thoroughly established. The scope and utility of this reaction have been extensively studied ...