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Listar por autor "Pino-Ángeles, Almudena"
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AMMO-Prot: Amine system project 3D-model finder
Navas-Delgado, Ismael; Pino-Ángeles, Almudena; Montañez, Raúl; Moya-García, Aurelio Ángel
; Urdiales-Ruiz, José Luis
; Sánchez-Jiménez, Francisca María
; Aldana-Montes, José Francisco
[et al.] (Springer Nature, 2008-04)
Background: Amines are biogenic amino acid derivatives, which play pleiotropic and very important yet complex roles in animal physiology. For many other relevant biomolecules, biochemical and molecular data are being ... -
Candidate Gene Study of TRAIL and TRAIL Receptors: Association with Response to Interferon Beta Therapy in Multiple Sclerosis Patients
López-Gómez, Carlos; Pino-Ángeles, Almudena; Órpez-Zafra, Teresa; Pinto-Medel, Mª Jesús; Oliver-Martos, Begoña; Ortega-Pinazo, Jesús; Arnáiz, Carlos; Guijarro-Castro, Cristina; Varadé, Jezabel; Alvarez-Lafuente, Roberto; Urcelay, Elena; Sánchez-Jiménez, Francisca María
; Fernández Fernández, Oscar; Leyva-Fernández, Laura
[et al.] (Public Library of Sciences, 2013)
TRAIL and TRAIL Receptor genes have been implicated in Multiple Sclerosis pathology as well as in the response to IFN beta therapy. The objective of our study was to evaluate the association of these genes in relation to ... -
Estudio de sistemas biológicos asociados a la membrana celular mediante una aproximación computacional
Pino-Ángeles, Almudena (2019-11-13)Más allá de mantener la integridad celular y actuar como primera barrera de protección, la membrana es lugar de residencia para aproximadamente el 30% de las proteínas en nuestro genoma. Además de estas proteínas, multitud ... -
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects
García-Vilas, Javier A.; Pino-Ángeles, Almudena; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María
; Medina-Torres, Miguel Ángel
(Elsevier, 2017-01)
The natural bioactive compound damnacanthal inhibits several tyrosine kinases. Herein, we show that -in fact- damancanthal is a multi kinase inhibitor. A docking and molecular dynamics simulation approach allows getting ...