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Listar por autor "Fuentes-Ríos, David"
Mostrando ítems 1-3 de 3
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Diastereoselective C-alkylation of aldimines, derived from chiral alpha-carbon heteroatom substituted aldehydes, with triethylborane. Application to the synthesis of benzylisoquinolines
Fuentes-Ríos, David; Muñoz, Carmen; Díaz-Morilla, Amelia; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel (Royal Society of Chemistry, 2023-03-13)The one-pot reaction of a chiral aldehyde, p-methoxyaniline or p-fluoroaniline, and triethylborane produces the corresponding alkylated chiral amine with high yields and distereoisomeric ratios. Stereocontrol is induced ... -
Isolation of Mycosporine-like Amino Acids from Red Macroalgae and a Marine Lichen by High-Performance Countercurrent Chromatography: A Strategy to Obtain Biological UV-Filters.
Vega Sánchez, Julia; Bárcenas-Pérez, Daniela; Fuentes-Ríos, David; López-Romero, Juan Manuel; Hrouzek, Pavel; López-Figueroa, Félix; Cheel, José[et al.] (MDPI, 2023-06-10)Marine organisms have gained considerable biotechnological interest in recent years due to their wide variety of bioactive compounds with potential applications. Mycosporine-like amino acids (MAAs) are UV-absorbing secondary ... -
n-Tuples on Scaffold Diversity Inspired by Drug Hybridisation to Enhance Drugability: Application to Cytarabine
García-Castro, Miguel; Fuentes-Ríos, David; López-Romero, Juan Manuel; Romero, Antonio; Moya-Utrera, Federico; Díaz-Morilla, Amelia; Sarabia-García, Francisco Ramón[et al.] (MDPI, 2023-12-13)A mathematical concept, n-tuples are originally applied to medicinal chemistry, especially with the creation of scaffold diversity inspired by the hybridisation of different commercial drugs with cytarabine, a synthetic ...