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LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor
Jongsma, Maikel; Matas-Rico, Elisa; Jalink, Kees; Moolenaar, Wouter H; Rzadkowski, Adrian (PLOS One, 2011-12)Lysophosphatidic acid (LPA), a lipid mediator enriched in serum, stimulates cell migration, proliferation and other functions in many cell types. LPA acts on six known G protein-coupled receptors, termed LPA1–6, showing ...