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Listar por autor "Gutierrez, Antonia"
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Amyloid-beta impairs TOM1-mediated IL-1R1 signaling
Cadete Martini, Alessandra; Gomez-Arboledas, Angela; Forner, Stefania; Rodriguez-Ortiz, Carlos; McQuade, Amanda; Danhash, Emma; Phan, Jimmy; Javoncillo, Dominic; Ha, Jordan-Vu; Tram, Melanie; Trujillo-Estrada, Laura Isabel; da Cunha, Celia; Ager, Rahasson; Davila, Jose Carlos; Kitazawa, Masashi; Blurton-Jones, Mathew; Gutierrez, Antonia; Baglietto-Vargas, David; Medeiros, Rodrigo; LaFerla, Frank M[et al.] (National Academy of Sciences, 2019-10)Defects in interleukin-1β (IL-1β)-mediated cellular responses contribute to Alzheimer's disease (AD). To decipher the mechanism associated with its pathogenesis, we investigated the molecular events associated with the ... -
Nuclear Translocation of Glutaminase GLS2 in Human Cancer Cells Associates with Proliferation Arrest and Differentiation
López de la Oliva, Amada; Campos-Sandoval, José A.; Gómez-García, María Carmen; Cardona, Carolina; Martín-Rufián, Mercedes; Sialana, Fernando J.; Castilla, Laura; Bae, Narkhyun; Lobo, Carolina; Peñalver, Ana; García-Frutos, Marina; Carro, David; Enrique, Victoria; Paz-Gutiérrez, José Carlos; Mirmira, Raghavendra G.; Gutiérrez, Antonia; Alonso-Carrión, Francisco José; Segura-Checa, Juan Antonio; Mates-Sánchez, José Manuel; Lubec, Gert; Márquez-Gómez, Javier[et al.] (Nature Portfolio, 2020-02-10)Glutaminase (GA) catalyzes the first step in mitochondrial glutaminolysis playing a key role in cancer metabolic reprogramming. Humans express two types of GA isoforms: GLS and GLS2. GLS isozymes have been consistently ...