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Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis
Palomares, Francisca; Aranda, Carlos José; Saenz de Santa María-García, Rocío; Mayorga Mayorga, Cristobalina; Rondón Segovia, Carmen; Testera Montes, Almudena; Alba-Linero, Carmen; Bentabol-Ramos, Guillermo; Torres-Jaén, María Josefa; Eguiluz-Gracia, Ibón[et al.] (Wiley, 2023)Key points ∙ Intranasal allergen exposure increases peripheral total Th2 and Th9 cells in patients with local allergic rhinitis (LAR). ∙ Peripheral T-cell response seems dominated by Th9 cells in patients with LAR, ... -
Aproximación diagnóstica a los diferentes fenotipos de rinitis de causa alérgica
Testera Montes, Almudena (UMA Editorial, 2021-12-16)Tradicionalmente la rinitis crónica se clasificaba en rinitis alérgica (RA) y rinitis no alérgica (RNA). Sin embargo, hasta un 25,7% de los pacientes diagnosticados inicialmente de RNA presentan rinitis alérgica local ... -
Biomarkers predicting the controller dose of omalizumab in patients with chronic spontaneous urticaria
Zubiaga- Fernandez, L.; Testera Montes, Almudena; Rondon, C.; Perez-Sanchez, N.; Gomez- Perez, F.; Vega-Chicote, J. M.; Bartra, Joan; Ferrer, M.; Eguiluz-Gracia, Ibón; Torres-Jaén, María Josefa[et al.] (Wiley, 2024-02-11)Background Clinical trials showed the efficacy of 300 mg/4 weeks of omalizumab (OMA) during 6 months in patients with severe chronic spontaneous urticaria (CSU). Nevertheless, in real life, many patients require higher ... -
Diagnosis and Treatment in Asthma and Allergic Rhinitis: Past, Present, and Future
Espada-Sánchez, Marta; Saenz de Santa María-García, Rocío; Martín Astorga, María del Carmen; Lebrón-Martín, Clara; Romero-Delgado, María-Jesús; Eguiluz-Gracia, Ibón; Rondón Segovia, Carmen; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Aranda, Carlos José; Cañas, José Antonio[et al.] (IOAP-MDPI, 2023-01-18)Respiratory diseases are pathological conditions that affect airways, hampering breathing and causing high mortality. In particular, asthma and allergic rhinitis (AR) are two of the most common airway diseases that affect ... -
Investigation of the diagnostic accuracy of basophil activation test for allergic phenotypes of rhinitis
Testera Montes, Almudena; Ariza Veguillas, Adriana; Sola-Martínez, Rosa Alba; Aranda, Carlos José; Bentabol-Ramos, Guillermo; Sánchez-Torralvo, Dulce; Mayorga Mayorga, Cristobalina; Torres-Jaén, María José; Eguiluz-Gracia, Ibón; Rondón Segovia, Carmen[et al.] (Wiley, 2024)Introduction: Basophil activation test (BAT) might be an alternative to nasal allergenchallenge (NAC) to identify the allergic etiology in rhinitis patients. Here, we investi-gate the diagnostic performance of BAT for ... -
Organ-specific allergen challenges in airway allergy: Current utilities and future directions
Fauquert, J. L.; Alba-Linero, Carmen; Gherasim, A.; Testera Montes, A.; Bentabol-Ramos, G.; Saenz de Santa María-García, Rocío; Torres-Jaén, María Josefa; Eguiluz-Gracia, Ibón; Rondon, C.[et al.] (Wiley, 2023)Atopy has been long used as the screening method for airway allergy. Nevertheless, aeroallergens can trigger respiratory symptoms not only in atopic patients (atopic res piratory allergy, ARA), but also in non-atopic ... -
Skin, gut, and lung barrier: physiological interface and target of intervention for preventing and treating allergic diseases
Berni Canani, Roberto; Caminati, Marco; Carucci, Laura; Eguiluz-Gracia, Ibón (Wiley, 2024-03-04)The epithelial barriers of the skin, gut, and respiratory tract are critical interfaces between the environment and the host, and they orchestrate both homeostatic and pathogenic immune responses. The ...