Listar por autor "Gil, Gregorio"
Mostrando ítems 1-2 de 2
-
PGC-1 alpha activates CYP7A1 and bile acid biosynthesis
Shin, Dong-Ju; Campos-Sandoval, José Ángel
; Gil, Gregorio; Osborne, Timothy F. (American Society for Biochemistry and Molecular Biology, 2003)
Cholesterol 7-alpha-hydroxylase (CYP7A1) is the key enzyme that commits cholesterol to the neutral bile acid biosynthesis pathway and is highly regulated. In the current studies, we have uncovered a role for the transcriptional ... -
The role of alpha1-fetoprotein transcription factor/LRH-1 in bile acid biosynthesis: a known nuclear receptor actovator that can act as a suppressor of bile acid biosynthesis
Del Castillo-Olivares, Antonio; Campos-Sandoval, José Ángel; Pandak, William M.; Gil, Gregorio (American Society for Biochemistry and Molecular Biology, 2004)
Two key regulatory enzymes in the bile acid biosynthesis pathway are cholesterol 7alpha-hydroxylase/CYP7A1 (7alpha-hydroxylase) and sterol 12alpha-hydroxylase/CYP8B1 (12alpha-hydroxylase). It has been shown previously that ...