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Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice
Rivaud, Mathilde R; Marchal, Gerard A; Wolswinkel, Rianne; Jansen, John A; van der Made, Ingeborg; Beekman, Leander; Ruiz-Villalba, Adrián; Baartscheer, Antonius; Rajamani, Sridharan; Belardinelli, Luiz; van Veen, Toon A B; Basso, Cristina; Thiene, Gaetano; Creemers, Esther E; Bezzina, Connie R; Remme, Carol Ann[et al.] (Oxford University Press, 2020)Aims: SCN5A mutations are associated with arrhythmia syndromes, including Brugada syndrome, long QT syndrome type 3 (LQT3), and cardiac conduction disease. Long QT syndrome type 3 patients display atrio-ventricular (AV) ...