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Deciphering the role of coumarin as a novel quorum sensing inhibitor suppressing virulence phenotypes in bacterial pathogens.
Gutiérrez Barranquero, José Antonio; Reen, F. Jerry; McCarthy, Ronan; O´Gara, Fergal (Springer Nature, 2015)The rapid unchecked rise in antibiotic resistance over the last few decades has led to an increased focus on the need for alternative therapeutic strategies for the treatment and clinical management of microbial infections. ... -
Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria
Gutiérrez Barranquero, José Antonio; Reen, F. Jerry; López Parages, María; McCarthy, Ronan; Dobson, Alan; O´Gara, Fergal[et al.] (Wiley, 2019)In recent years, the marine environment has been the subject of increasing attention from biotechnological and pharmaceutical industries. A combination of unique physicochemical properties and spatial niche-specific ...