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Recombinant IGF-1 Induces Sex-Specific Changes in Bone Composition and Remodeling in Adult Mice with Pappa2 Deficiency
Rubio-Lamia, Leticia Olga; Vargas, Antonio; River, Patricia; López-Gambero, Antonio J.; Tobar, Rubén; Christians, Julian K.; Martín-de-las-Heras, Stella; Rodriguez-de-Fonseca, Fernando; Chowen, Julie A.; Argente, Jesús; Suárez-Pérez, Juan[et al.] (MDPI, 2021)Deficiency of pregnancy-associated plasma protein-A2 (PAPP-A2), an IGF-1 availability regulator, causes postnatal growth failure and dysregulation of bone size and density. The present study aimed to determine the effects ...