Listar por autor "Mayorga Mayorga, Cristobalina"
Mostrando ítems 1-16 de 16
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Advances and highlights in T and B cell responses to drug antigens
Fernandez-Santamaría, Rubén; Ariza Veguillas, Adriana; Fernández-Duarte, Tahía Diana
; Cespedes, Jose Antonio; Labella, Marina; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-07)
The immunological mechanisms involved in drug hypersensitivity reactions (DHRs) are complex, and despite important advances, multiple aspects remain poorly understood. These not fully known aspects are mainly related to ... -
Basophil Activation Test Utility as a Diagnostic Tool in LTP Allergy
Cañas, José Antonio; Pérez-Sánchez, Natalia; Palomares, Francisca; Molina, Ana; Bartra, Joan; Torres-Jaén, María Josefa; Gómez, Francisca; Mayorga Mayorga, Cristobalina[et al.] (IOAP-MPDI, 2022-04-29)
Plant-food allergy is an increasing problem, with nonspecific lipid transfer proteins (nsLTPs) triggering mild/severe reactions. Pru p 3 is the major sensitizer in LTP food allergy (FA). However, in vivo and in vitro ... -
Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
Matamoros Castellano, Esther; Jimenez, Isabel M.; Gil-Ocaña, Violeta; Mayorga Mayorga, Cristobalina; Doña, Inmaculada; Cespedes, Jose Antonio; Montañez-Vega, María Isabel; Vida-Pol, Yolanda; Pérez-de-Inestrosa-Villatoro, Ezequiel; Torres-Cazorla, María Isabel[et al.] (2022)
Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
Nájera-Albendín, Francisco; Montañez-Vega, María Isabel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Mayorga Mayorga, Cristobalina; Torres, María José; Blanca Gómez, Miguel[et al.] (2014-06-12)
Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Detection of Serum-Specific IgE by Fluoro-Enzyme Immunoassay for Diagnosing Type I Hypersensitivity Reactions to Penicillins
Ariza Veguillas, Adriana; Mayorga Mayorga, Cristobalina; Bogas Herrera, Gádor; Gaeta, Francesco; Salas, María; Valluzzi, Rocco Luigi; Labella, Marina; Pérez-Sánchez, Natalia; Caruso, Cristiano; Molina, Ana; Fernández-Duarte, Tahía Diana; Torres-Jaén, María Josefa; Romano, Antonino[et al.] (IOAP-MPDI, 2022-06-23)
Diagnosis of type I hypersensitivity reactions (IgE-mediated reactions) to penicillins is based on clinical history, skin tests (STs), and drug provocation tests (DPTs). Among in vitro complementary tests, the fluoro-enzyme ... -
Diagnosis and Treatment in Asthma and Allergic Rhinitis: Past, Present, and Future
Espada-Sánchez, Marta; Sáenz de Santa María, Rocío; Martín Astorga, María del Carmen; Lebrón-Martín, Clara; Romero-Delgado, María-Jesús; Eguiluz-Gracia, Ibón; Rondón Segovia, Carmen; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Aranda, Carlos José; Cañas, José Antonio[et al.] (IOAP-MDPI, 2023-01-18)
Respiratory diseases are pathological conditions that affect airways, hampering breathing and causing high mortality. In particular, asthma and allergic rhinitis (AR) are two of the most common airway diseases that affect ... -
Diagnosis of immediate reactions to amoxicillin: Comparison of basophil activation markers CD63 and CD203c in a prospective study
Céspedes, Jose Antonio; Fernandez-Santamaría, Rubén; Ariza Veguillas, Adriana; Bogas Herrera, Gádor; Doña, Inmaculada; Rondón, Carmen; Salas, María; Labella, Marina; Frecha, Cecilia; Mayorga Mayorga, Cristobalina; Torres, Maria J; Fernández-Duarte, Tahía Diana[et al.] (Wiley, 2022-12-07)
Amoxicillin (AX) combined or not with clavulanic acid (CLV) is frequently involved in IgE-mediated reactions. Drug provocation test (DPT) is considered as the gold standard for diagnosis, although contraindicated in high-risk ... -
Direct characterization of functional materials by haptenized fluorescent dendrimers for in vitro allergic drug diagnose
Ruiz-Sanchez, Antonio Jesus; Collado-Martín, Daniel; Mayorga Mayorga, Cristobalina; Torres, Maria J.; Pérez-de-Inestrosa-Villatoro, Ezequiel (2020-10-01)
β-lactams are the most widely drug prescribed against infections, but they are the most commonly reported medication allergy too. A correct diagnosis of these allergic reactions is crucial to avoid rejecting them by other ... -
Estudio de los mecanismos inmunológicos implicados en la inmunoterapia específica con alérgenos. Papel de las células T reguladoras y efectoras específicas
(UMA Editorial, 2018)Dentro de las reacciones alérgicas originadas en las vías respiratorias, la rinitis alérgica (RA) es la que cobra mayor importancia en cuanto a su incidencia en la población. Entre los alérgenos más prevalentes en esta ... -
Estudios de la modulación de la respuesta inmunológica y desarrollo de modelos de tolerancia a alérgenos de origen vegetal utilizando nanoestructuras polifuncionales
(UMA Editorial, 2020)La alergia a alimentos es en la actualidad un problema de salud grave, ya que produce reacciones que pueden comprometer la vida del paciente. Su prevalencia va en aumento, llegando a afectar al 3-5% de la población adulta ... -
Influence of pore size in protein G'-grafted mesoporous silica nanoparticles as a serum pretreatment system for in vitro allergy diagnosis
Paris, Juan L.; Monío, Cristina; Pérez-Moreno, Ana M.; Jurado-Escobar, Raquel; Bogas Herrera, Gádor; Fernández-Duarte, Tahía Diana; Montañez-Vega, María Isabel; Mayorga Mayorga, Cristobalina; Torres, María J.[et al.] (Wiley, 2023)
Particles with the capacity to bind to immunoglobulin G (IgG) can be used for the purification of IgG or to process clinical samples for diagnostic purposes. For in vitro allergy diagnosis, the high IgG levels in serum can ... -
New Approaches in the Manufacture of Biomaterials for Betalactam Allergic Diagnose
Collado-Martín, Daniel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Ruiz-Sanchez, Antonio Jesus; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa (2019-09-11)
Betalactams are the most widely utilized drugs against infections but are the primary cause of allergic reactions to antibiotic drugs. REF1 An accurate diagnosis of these allergic reactions to betalactams is crucial to ... -
Perfil de sensibilización en pacientes con alergia a melocotón, y estudio de los cambios inmunológicos, eficacia y tolerancia a inmunoterapia específica con melocotón
(UMA Editorial, 2016)Aproximadamente el 2% de la población adulta es alérgica a alimentos, fundamentalmente a vegetales, siendo la familia de las Rosaceae la más frecuentemente implicada (1,2,3,4,5,6,7). La alergia a alimentos tiene un gran ... -
Synthetic antigenic determinants of clavulanic acid induce dendritic cell maturation and specific T cell proliferation in patients with immediate hypersensitivity reactions
Fernandez-Santamaría, Rubén; Bogas Herrera, Gádor; Montañez-Vega, María Isabel; Ariza Veguillas, Adriana; Salas, María; Cespedes, Jose Antonio; Labella, Marina; Paris, Juan Luis; Perez Sanchez, Natalia Isabel; Pérez-de-Inestrosa-Villatoro, Ezequiel; Vida-Pol, Yolanda; Fernández-Duarte, Tahía Diana; Mayorga Mayorga, Cristobalina[et al.] (Wiley, 2022-05-24)
Background Immediate drug hypersensitivity reactions (IDHRs) to clavulanic acid (CLV) have increased in the last decades due to a higher consumption alongside amoxicillin (AX). Due to its chemical instability, diagnostic ... -
The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine
Marina, Labella; Cespedes, Jose Antonio; Doña, Inmaculada; Shamji, Mohamed H.; Agache, Ioana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-24)
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Usefulness of myeloid dendritic cells in cellular in vitro assays for evaluating immediate hypersensitivity reactions to betalactams.
Fernandez-Santamaría, Rubén; Ariza Veguillas, Adriana; Bogas Herrera, Gádor; Salas, María; Calvo-Serrano, Silvia; Frecha, Cecilia; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Fernández-Duarte, Tahía Diana[et al.] (2023)
Introduction Dendritic cells (DCs) are the most potent antigen presenting cells (APCs) with an important role detecting, processing, and presenting antigens to T cells. The analysis of maturation after in vitro stimulation ...