Listar por autor "Mayorga, Cristobalina"
Mostrando ítems 1-9 de 9
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An algorithm for the diagnosis of beta-lactam allergy, 2024 update
(Wiley, 2024-10) -
Basophil activation test is a complementary tool in the diagnosis of immediate reactions to platinum salts and taxanes
(Wiley, 2024)Background Delabelling pathways offer confirmatory diagnosis and can prevent unnecessary second-line therapies or drug desensitization procedures after chemotherapeutic hypersensitivity reactions (CHT-HSRs). However, these ... -
Dendrimeric Antigens. New Approaches Towards Detection of IgE‐Mediated Drug Allergy Reactions
Montañez-Vega, María Isabel
; Mayorga, Cristobalina; Torres-Jaén, María Josefa; Ruiz-Sánchez, Antonio Jesús; Malkoch, M; Hult, A; Blanca, Miguel; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (RSC Publishing, 2013-05-31)
Drugs are low molecular weight substances which cannot cause an immune response on their own. However, they can act as haptens and form covalent adducts with proteins. The resulting hapten‐carrier (drug‐protein) conjugate ... -
Direct Single-Dose Drug-Provocation Test Is Safe for Delabelling Penicillin Low-Risk Reactions in Adults
Labella, Marina; Rodriguez de Guzmán, Julia; Diez-Echave, Patricia; Salas, María; Fernández-Santamaría, Rubén; Mayorga, Cristobalina; Doña, Inmaculada; Torres-Jaén, María Josefa[et al.] (Wiley, 2025)
Background: Penicillins (PENs) are the most frequent drug-allergic reactions trigger. However, diagnostic work-up is complex and time-consuming: it requires skin testing (ST) and drug-provocation test (DPT), needing faster ... -
Identification of an Antigenic Determinant of Clavulanic Acid Responsible for IgE‐mediated Reactions
Barbero, Nekane; Fernández-Santamaría, Rubén; Mayorga, Cristobalina; Martín-Serrano Ortiz, Ángela; Salas, Maria; Bogas, Gador; Nájera-Albendín, Francisco; Pérez-Sala, Dolores; Perez-Inestrosa, Ezequiel; Fernandez, Tahia D; Montañez-Vega, María Isabel; Torres, Maria J[et al.] (John Wiley and Sons Ltd., 2019)
Background: Selective reactions to clavulanic acid (CLV) account for around 30% of immediate reactions after administration of amoxicillin‐CLV. Currently, no immunoas‐ say is available for detecting specific IgE to CLV, ... -
Multiepitope Dendrimeric Antigen-Silica particle composites as nano-based platforms for specific recognition of IgEs
Gil-Ocaña, Violeta; Jimenez, Isabel M.; Mayorga, Cristobalina; Doña, Inmaculada; Cespedes, Jose A.; Montañez, Maria I.; Vida-Pol, Yolanda; Torres, Maria J.; Perez-Inestrosa, Ezequiel[et al.] (Frontiers, 2021)
β-lactam antibiotics (BLs) are the drugs most frequently involved in drug hypersensitivity reactions. However, current in vitro diagnostic tests have limited sensitivity, partly due to a poor understanding of in vivo ... -
Recognition of multiepitope dendrimeric antigens by human immunoglobulin E.
Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Mayorga, Cristobalina; Ruiz-Sánchez, Antonio Jesús; Vida-Pol, Yolanda; Collado-Martín, Daniel; Blanca, Miguel; Torres-Jaén, María Josefa; Pérez-de-Inestrosa-Villatoro, Ezequiel[et al.] (Elsevier, 2015-02-07)
In vitro drug allergy tests have limited sensitivity, partly due to a poor understanding of the immunological recognition of in vitro drug–protein conjugates. We have designed and synthesized multivalent mono- and bi-epitope ... -
The Role of Benzylpenicilloyl Epimers in Specific IgE Recognition
Mayorga, Cristobalina; Montañez-Vega, María Isabel; Nájera-Albendín, Francisco; Bogas Herrera, Gádor; Rodriguez Gil, David; Palacios, Ricardo; Torres-Jaén, María Josefa; Vida-Pol, Yolanda; Perez-Inestrosa, Ezequiel[et al.] (Frontiers, 2021)
The high prevalence of allergy to β-lactam antibiotics is a worldwide issue. Accuracy of diagnostic methods is important to prove tolerance or allergy, with skin test considered the best validated in vivo method for ... -
Transcriptional profiling of dendritic cells in a mouse model of food-antigen induced anaphylaxis reveals the upregulation of multiple immune-related pathways.
Rodríguez, María José; Palomares, Francisca; Bogas, Gador; Torres-Jaén, María Josefa; Díaz-Perales, Araceli; Rojo, Javier; Plaza Serón, María del Carmen; Rodríguez-Nogales, Alba; Orengo, Christine A.; Mayorga, Cristobalina; Perkins, James Richard[et al.] (Wiley, 2018-10-20)
Scope Much of our knowledge about gene expression during anaphylaxis comes from candidate gene studies. Despite their potential role, expression changes in dendritic cells (DCs) have not been studied in this context using ...