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Role of severe acute respiratory syndrome Coronavirus Viroporins E, 3a, and 8a in replication and pathogenesis
Castaño-Rodriguez, Carlos; Honrubia, José M.; Gutiérrez-Álvarez, Javier; DeDiego, Marta L.; Nieto-Torres, Jose Luis; Jimenez-Guardeño, Jose Manuel; Regla-Nava, Jose Angel; Fernandez-Delgado, Raul; Verdiá-Báguena, Carmina; Queralt-Martín, María; Kochan, Grazyna; Perlman, Stanley; Aguilella, Vicente M; Sola, Isabel; Enjuanes, Luis[et al.] (American Society for Microbiology, 2018)Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis. While many coronaviruses (CoVs) encode two viroporins, severe ...