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Listar por autor "Ramos, Juan Luis"
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Differential transcriptional response to antibiotics by Pseudomonas putida DOT-T1E
Molina-Santiago, Carlos; Daddaoua, Abdelali; Gómez-Lozano, María; Udaondo, Zulema; Molin, Soren; Ramos, Juan-Luis[et al.] (Wiley, 2015)Multi-drug resistant bacteria are a major threat to humanity, especially because the current battery of known antibiotics is not sufficient to combat infections produced by these microbes. Therefore, the study of how current ... -
Draft whole-genome sequence of the antibiotic-producing soil isolate Pseudomonas sp. strain 250J
Molina-Santiago, Carlos; Udaondo, Zulema; Ramos, Juan-Luis (Wiley, 2014)Bacteria of the genus Pseudomonas are becoming increasing well known for their ability to produce a wide range of antimicrobial compounds. In a largescale screening for antibiotic producers, we identified a soil isolate ... -
Efflux pump-deficient mutants as a platform to search for microbes that produce antibiotics
Molina-Santiago, Carlos; Udaondo, Zulema; Daddaoua, Abdelali; Roca, Amalia; Martín, Jesús; Pérez-Victoria, Ignacio; Reyes, Fernando; Ramos, Juan Luis[et al.] (Wiley, 2015-01-08)Pseudomonas putida DOT-T1E-18 is a strain deficient in the major antibiotic efflux pump (TtgABC) that exhibits an overall increased susceptibility to a wide range of drugs when compared with the wild-type strain. We used ... -
Identification of new residues involved in intramolecular signal transmission in a prokaryotic transcriptional repressor
Molina-Santiago, Carlos; Daddaoua, Abdelali; Fillet, Sandy; Krell, Tino; Morel, Bertrand; Duque, Estrella; Ramos, Juan Luis[et al.] (American Society for Microbiology, 2014-01-09) -
Interspecies signalling: Pseudomonas putida efflux pump TtgGHI is activated by indole to increase antibiotic resistance
Molina-Santiago, Carlos; Daddaoua, Abdelali; Fillet, Sandy; Duque, Estrella; Ramos, Juan Luis (Wiley, 2013-12-14)In Gram-negative bacteria, multidrug efflux pumps are responsible for the extrusion of chemicals that are deleterious for growth. Some of these efflux pumps are induced by endogenously produced effectors, while abiotic or ...