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Listar por autor "Narváez, Manuel"
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Enhancing Cognitive Functions and Neuronal Growth through NPY1R Agonist and Ketamine Co-Administration: Evidence for NPY1R-TrkB Heteroreceptor Complexes in Rats
Arrabal-Gómez, José Carlos; Rasiel, Beltran-Casanueva; Hernández-García, Aracelis; Bayolo-Guanche, Juan Vicente; Barbancho-Fernández, Miguel Ángel; Serrano-Castro, Pedro Jesús; Narváez, Manuel[et al.] (2024-04-12)This study investigates the combined effects of the neuropeptide Y Y1 receptor (NPY1R) agonist [Leu31-Pro34]NPY at a dose of 132 g and Ketamine at 10 mg/Kg on cognitive functions and neuronal proliferation, against a ... -
Neuropeptide Y receptor 1 and galanin receptor 2 (NPY1R-GALR2) interactions in the dentate gyrus and their relevance for neurogenesis and cognition
Beltran-Casanueva, Rasiel; Hernández-García, Aracelis; de Amo García, Paula; Blanco-Reina, Encarnación; Serrano-Castro, Pedro; García-Casares, Natalia; Fuxe, Kjell; Borroto-Escuela, Dasiel O.; Narváez, Manuel[et al.] (2024-02-14)Introduction: This study may unveil novel insights into the interactions between neuropeptide Y receptor 1 (NPY1R) and galanin receptor 2 (GALR2), in the dentate gyrus of the dorsal hippocampus, shedding light on their ... -
Potentiation of antidepressant effects: NPY1R agonist and ketamine synergy enhances TrkB signaling and neurogenesis in the ventral hippocampus
Arrabal-Gómez, Carlos; Serrano-Castro, Pedro; Sánchez-Pérez, José Andrés; Garcia-Casares, Natalia; Fuxe, Kjell; Borroto-Escuela, Dasiel; Narváez, Manuel[et al.] (Taylor & Francis, 2024-04-18)Background: Major Depressive Disorder (MDD) poses a significant challenge to global health, with current treatments often limited by efficacy and onset delays. This study explores the synergistic antidepressant-like effects ...