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Listar por autor "Fernández, Javier"
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Cardiovascular Modeling Software Tools in Medicine
Fernández, Javier; Fernández de Cañete, Rafael; Perea-Paizal, Julia; Ramos-Diaz, Juan Carlos (2017-10-09)The high prevalence of cardiovascular diseases has provoked a raising interest in the development of mathematical models in order to evaluate the cardiovascular function both under physiological and pathological conditions. ... -
Causal Modeling of the Glucose-Insulin System in Type-I Diabetic Patients
Fernández, Javier; Aguilar-Pérez, Natalia; Fernández de Cañete, Rafael; Ramos-Diaz, Juan Carlos (2017-10-06)In this paper, a simulation model of the glucoseinsulin system for a patient undergoing diabetes Type 1 is developed by using a causal modeling approach under system dynamics. The OpenModelica simulation environment has ... -
Expression of the skin-homing receptor in peripheral blood lymphocytes from subjects with nonimmediate cutaneous allergic drug reactions
Blanca, Miguel; Posadas, Sinforiano Jose; Torres-Jaén, María Josefa; Leyva-Fernández, Laura; Mayorga Mayorga, Cristobalina; González, Lourdes; Juárez, Carlos; Fernández, Javier; Santamaría, Luis F[et al.] (Wiley, 2000)Background: In nonimmediate cutaneous reactions to drugs, the skin is the organ most frequently involved, and T lymphocytes may play a relevant role. T cells related to skin immune responses express the cutaneous ... -
Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction
Posadas, Sinforiano Jose; Leyva-Fernández, Laura; Torres-Jaén, María Josefa; Rodríguez-Bada, José Luis; Bravo, Inmaculada; Rosal, Manuel; Fernández, Javier; Juárez, Carlos; Blanca, Miguel[et al.] (Elsevier, 2000-10)Background: The mechanisms involved in adverse drug reactions with an immunologic basis (ADRIB) can be antibody dependent, mainly IgE or T cell dependent (sensitized T cells). These mechanisms are regulated by a number of ...