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TRIM5-mediated retrovirus restriction is modulated by type I interferon.
Ortega-Prieto, Ana María; Boehmer, Nina; Dinc, Hanife; Betancor, Gilberto; Petrosyan, Eduard; Malim, Michael H.; Jiménez-Guardeño, José Manuel[et al.] (2024)Since the identification in 2004 of the interferon-stimulated gene (ISG) tripartite motif-containing protein 5 α (TRIM5α) from rhesus macaques as a restriction factor preventing HIV-1 infection in these monkeys, the ...