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Listar por autor "Fuentes-Ríos, David"
Mostrando ítems 1-5 de 5
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Diastereoselective C-alkylation of aldimines, derived from chiral alpha-carbon heteroatom substituted aldehydes, with triethylborane. Application to the synthesis of benzylisoquinolines
Fuentes-Ríos, David; Muñoz, Carmen; Díaz-Morilla, Amelia; Sarabia-García, Francisco Ramón
; López-Romero, Juan Manuel
(Royal Society of Chemistry, 2023-03-13)
The one-pot reaction of a chiral aldehyde, p-methoxyaniline or p-fluoroaniline, and triethylborane produces the corresponding alkylated chiral amine with high yields and distereoisomeric ratios. Stereocontrol is induced ... -
Isolation of Mycosporine-like Amino Acids from Red Macroalgae and a Marine Lichen by High-Performance Countercurrent Chromatography: A Strategy to Obtain Biological UV-Filters.
Vega Sánchez, Julia; Bárcenas-Pérez, Daniela; Fuentes-Ríos, David; López-Romero, Juan Manuel; Hrouzek, Pavel; López-Figueroa, Félix
; Cheel, José[et al.] (MDPI, 2023-06-10)
Marine organisms have gained considerable biotechnological interest in recent years due to their wide variety of bioactive compounds with potential applications. Mycosporine-like amino acids (MAAs) are UV-absorbing secondary ... -
n-Tuples on Scaffold Diversity Inspired by Drug Hybridisation to Enhance Drugability: Application to Cytarabine
García-Castro, Miguel; Fuentes-Ríos, David; López-Romero, Juan Manuel; Romero, Antonio; Moya-Utrera, Federico; Díaz-Morilla, Amelia
; Sarabia-García, Francisco Ramón
[et al.] (MDPI, 2023-12-13)
A mathematical concept, n-tuples are originally applied to medicinal chemistry, especially with the creation of scaffold diversity inspired by the hybridisation of different commercial drugs with cytarabine, a synthetic ... -
Synthesis of (-)-cannabidiol (CBD),(-)-Δ9- and(-)--Δ8-tetrahydrocannabinols, encapsulation of CBD with nanoparticles for controlled delivery and biological evaluation
Moya-Utrera, Federico; Fuentes-Ríos, David; Romero-Carrasco, Antonio; Doña Flores, Manuel; Cheng-Sánchez, Iván; Díaz-Morilla, Amelia; Pino-González, María Soledad
; Martínez-Férez, Antonio; Moreno, Javier; Mesas, Cristina; Melguizo, Consolación; Prados, José; Sarabia-García, Francisco Ramón
; López-Romero, Juan Manuel
[et al.] (Wiley, 2024-12)
Cannabidiol (CBD) is garnering increasing interest due to its significant biological activity. This natural compound is one of the major cannabinoids in Cannabis sativa L. In this work, we describe the encapsulation of CBD ... -
Synthesis, characterization and antitumor activity of a poly-4-Vinyl pyridine-co-cannabidiol polymer
Fuentes-Ríos, David; Moya-Utrera, Federico; Moreno, Javier; Mesas, Cristina; Doña Flores, Manuel; Sarabia-García, Francisco Ramón; López-Romero, Juan Manuel
; Melguizo, Consolación; Prados, José[et al.] (Elsevier, 2024)
Due to its natural origin and numerous beneficial properties, cannabidiol (CBD), one of the major phytocannabinoids of the Cannabis sativa L., has attracted the attention of many research groups in recent years. In this ...