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Listar por autor "De Luque, Vanessa"
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A microRNA signature associated with early recurrence in breast cancer.
Pérez-Rivas, Luis G.; Jerez-Aragonés, José Manuel; Carmona, Rosario; De Luque, Vanessa; Vicioso-Recio, Luis Prudencio; Claros-Díaz, Manuel Gonzalo; Viguera-Mínguez, Enrique; Pajares, Bella; Sánchez-Muñoz, Alfonso; Ribelles, Nuria; Alba-Conejo, Emilio; Lozano-Castro, José[et al.] (PLOS, 2014-03-14)Recurrent breast cancer occurring after the initial treatment is associated with poor outcome. A bimodal relapse pattern after surgery for primary tumor has been described with peaks of early and late recurrence occurring ... -
Efecto de la quimioterapia neoadyuvante en la variación de receptores hormonales, Her2 y Ki67 en pacientes con cáncer de mama
Álvarez-Pérez, Martína; Lavado-Fernández, Ana Isabel; Pérez-Villa, Lidia; Lozano, María José; Jiménez-Rodríguez, Begoña; De Luque, Vanessa; Jiménez-Vista, Álvaro; Ventura, Carmen; Jiménez-Fernández, Ana; Rodrigo-Fernández, Isabel; Ramírez-Tortosa, César; Ribelles, Nuria; Alba-Conejo, Emilio; Vicioso-Recio, Luis Prudencio[et al.] (2016-03-02)Introducción:Existe controversia respecto al impacto de la quimioterapia en la expresión de marcadores inmunohistoquímicos del cáncer de mama, ya que pueden existir cambios en los marcadores tumorales entre las biopsias ... -
Estudio de factores predictivos de respuesta patológica a quimioterapia neoadyuvante en el cáncer de mama receptores hormonales positivos HER2 negativo
Lavado-Fernández, Ana Isabel; Álvarez-Pérez, Martína; Prieto Cuadra, Juan Daniel; Jiménez-Rodríguez, Begoña; Lozano, María José; De Luque, Vanessa; Jiménez-Vista, Álvaro; Ventura, Carmen; Jiménez-Fernández, Ana; Rodrigo, Isabel; Ramírez, César; Cano, Tatiana; González-Zafra, Virginia; Pérez-Villa, Lidia; Gallego-Domínguez, Elena María; Ortega-Jiménez, María Victoria; Arranz-Salas, Isabel María; Ribelles, Nuria; Alba-Conejo, Emilio; Vicioso-Recio, Luis Prudencio[et al.] (2015-07-02)La quimioterapia neoadyuvante (QTN) se utiliza cada vez más para conseguir una reducción tumoral que permita una cirugía conservadora y, mediante el grado de respuesta patológica tumoral, determinar el pronóstico de las ... -
Fingolimod phosphate protection against mitochondrial damage in neuronal cells
Martín-Montañez, Elisa; Gil Cebrián, Antonio Jesús; Valverde, Nadia; Lara, Estrella; De Luque, Vanessa; Boraldi, Federica; Urbano, María; García-Fernández, María Inmaculada; Pavía-Molina, José[et al.] (Elsevier, 2019-04-17)Background: Major role of oxidative stress in the pathogenesis of neurodegenerative diseases have been suggested, being mitochondria one of the main sources of ROS. Aim: In the present work, we have studied the antioxidant ... -
IGF-II as a neuroprotective and neuroplastic factor in an oxidative damage model induced by glucocorticoids
Lara Fernández, Estrella; Valverde, Nadia; De Luque, Vanessa; Boraldi, Federica; Santín-Núñez, Luis Javier; Pavía-Molina, José; Martín-Montañez, Elisa; García-Fernández, María Inmaculada[et al.] (2018-10-11)IGF-II is a pleiotropic hormone widely distributed in the CNS, which triggers its functions by binding to IGF-IR, InsulinR and IGFII / M6P (IGF-IIR) receptors. Recently, it has been proposed that the effects of IGF-II, ... -
Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
Sánchez-Muñoz, Alfonso; Gallego-Domínguez, Elena María; De Luque, Vanessa; Pérez-Rivas, Luis G.; Vicioso-Recio, Luis Prudencio; Ribelles, Nuria; Lozano-Castro, José; Alba-Conejo, Emilio[et al.] (Springer Nature, 2010-04-13)Background: Mutational analysis of the KRAS gene has recently been established as a complementary in vitro diagnostic tool for the identification of patients with colorectal cancer who will not benefit from anti-epidermal ... -
Male breast cancer: correlation between immunohistochemical subtyping and PAM50 intrinsic subtypes, and the subsequent clinical outcomes
Sánchez-Muñoz, Alfonso; Vicioso-Recio, Luis Prudencio; Santonja, Angela; Alvaréz, Martina; Plata-Fernández, Yéssica; Miramón, José; Zarcos, Irene; Ramírez-Tortosa, César; Montes-Torres, Julio; Jerez-Aragonés, José Manuel; De Luque, Vanessa; Llácer, Casilda; Fernández-De Sousa, C.E.; Pérez-Villa, Lidia; Alba-Conejo, Emilio[et al.] (Elsevier, 2018-02)Male breast cancer is a rare disease that is still poorly understood. It is mainly classified by immunohistochemistry as a luminal disease. In this study, we assess for the first time the correlation between molecular ... -
Male breast cancer: correlation between immunohistochemical subtyping and PAM50 intrinsic subtypes, and the subsequent clinical outcomes.
Sánchez-Muñoz, Alfonso; Vicioso-Recio, Luis Prudencio; Santonja, Ángela; Álvarez-Pérez, Martína; Plata-Fernández, Yéssica; Miramón, José; Zarcos, Irene; Ramírez-Tortosa, C.L.; Montes-Torres, Julio; Jérez, J.M.; De Luque, Vanessa; Llácer, Casilda; Fernández-De Sousa, C.E.; Pérez-Villa, Lidia; Alba-Conejo, Emilio[et al.] (Elsevier, 2017-09-22)Male breast cancer is a rare disease that is still poorly understood. It is mainly classified by immunohistochemistry as a luminal disease. In this study, we assess for the first time the correlation between molecular ... -
Papel del receptor S1P sobre el estrés oxidativo mitocondrial en cultivo neuronal
Valverde, Nadia; Lara, Estrella; Gil Cebrián, Antonio Jesús; De Luque, Vanessa; Boraldi, Federica; Pavía-Molina, José; Fernández, Oscar; Martín-Montañez, Elisa; García-Fernández, María Inmaculada[et al.] (2019-06-25)Introducción: Fingolimod, fármaco inmunomodulador, presenta propiedades neuroprotectoras que podrían promover la recuperación de la función cognitiva en enfermedades neurodegenerativas. El estrés oxidativo parece tener un ... -
Pattern of recurrence of early breast cancer is different according to intrinsic subtype and proliferation index.
Ribelles, Nuria; Jerez-Aragonés, José Manuel; Pajares, Bella; Vicioso-Recio, Luis Prudencio; Jiménez-Rodríguez, Begoña; De Luque, Vanessa; Franco, Leónardo; Gallego-Domínguez, Elena María; Márquez, Antonia; Álvarez, Martina; Sánchez-Muñoz, Alfonso; Pérez-Rivas, Luis G.; Alba-Conejo, Emilio; Ribelles, Nuria[et al.] (BMC, 2013-10-22)Recurrence risk in breast cancer varies throughout the follow-up time. We examined if these changes are related to the level of expression of the proliferation pathway and intrinsic subtypes. Results: Luminal A displayed ... -
Serum protein levels following surgery in breast cancer patients: A protein microarray approach
Pérez-Rivas, Luis G.; Jérez, J.M.; Fernández-De Sousa, C.E.; De Luque, Vanessa; Quero, C.; Pajares, Bella; Franco, L.; Sánchez-Muñoz, Alfonso; Ribelles, Nuria; Alba-Conejo, Emilio[et al.] (Spandidos Publications, 2012-07)Surgery is the primary treatment for non-metastatic breast cancer. However, the risk of early recurrence remains after surgical removal of the primary tumor. Recurrence is suggested to result from hidden micrometastatic ... -
Triple negative breast cancer subtypes and pathologic complete response rate to neoadjuvant chemotherapy.
Santonja, Ángela; Sánchez-Muñoz, Alfonso; Lluch, Ana; Chica Parrado, María del Rosario; Albanell, J.; Chacón, José Ignacio; Antolín, Silvia; Jerez-Aragonés, José Manuel; De la Haba, Juan; De Luque, Vanessa; Fernández-De-Sousa, Cristina Elisabeth; Vicioso-Recio, Luis Prudencio; Plata-Fernández, Yéssica; Ramírez-Tortosa, César; Álvarez-Pérez, Martína; Llácer, Casilda; Zarcos-Pedrinaci, Irene; Carrasco, Eva; Caballero, Rosalía; Martín, Miguel; Alba-Conejo, Emilio[et al.] (Impact Journals, 2018-05-29)Triple negative breast cancer (TNBC) is a heterogeneous disease with distinct molecular subtypes that differentially respond to chemotherapy and targeted agents. The purpose of this study is to explore the clinical ...