Listar por autor "Vivar García, Carlos"
Mostrando ítems 1-4 de 4
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Epi-, epoxy- and C2-modified bengamides: Synthesis and biological Evaluation
Sarabia-García, Francisco Ramón
; Martín-Gálvez, Francisca; García-Ruiz, Cristina; Sánchez-Ruiz, Antonio; Vivar García, Carlos (ACS, 2013)
With the objective of investigating the influence of structural modifications of the polyketide chain of the bengamides upon their antitumoral activities, we targeted the preparation of bengamide E analogues with modification ... -
Exploring the chemistry of epoxy amides for the synthesis of the 2"-epi-diazepanone core of liposidomycins and caprazamycins
Sarabia-García, Francisco Ramón; Vivar García, Carlos; García-Ruiz, Cristina; Martín Ortiz, Laura; Romero-Carrasco, Antonio (ACS, 2012)
New synthetic strategies have been explored for the synthesis of the structural core of liposidomycins and caprazamycins, an intriguing class of complex nucleoside-type antibiotics. This structural core is comprised of a ... -
Exploring the reactivity of chiral glycidic amides for their applications in synthesis of bioactive compounds.
Sarabia-García, Francisco Ramón; Vivar García, Carlos; García-Ruiz, Cristina; Sánchez-Ruiz, Antonio; Pino-González, María Soledad; García-Castro, Miguel; Chammaa, Samy[et al.] (Wiley, 2014-05)
A new class of chiral sulfonium salts, derived from L- and D-methionine, has been designed and successfully employed in our laboratories for the diastereoselective synthesis of glycidic amides. The epoxy amides obtained ... -
Síntesis estereoselectiva de amidas glicídicas vía una nueva clase de sales de sulfonio quirales: aplicaciones en síntesis de productos naturales
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)En esta tesis se explora una nueva metodología de síntesis asimétrica de epóxidos mediante el uso de una nueva clase de sales de sulfonio quirales derivadas de aminoácidos y caracterizadas por una estructura bicíclica. Las ...