Listar por autor "González-Jiménez, Andrés"
Mostrando ítems 1-11 de 11
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A revised electronic version of RUCAM for the diagnosis of DILI
Hayashi, Paul H.; Lucena-González, María Isabel
; Fontana, Robert J.; Bjornsson, Einar S.; Aithal, Guruprasad P.; Barnhart, Huiman; González-Jiménez, Andrés; Yang, Qinghong; Gu, Jiezhun; Andrade-Bellido, Raúl Jesús; Hoofnagle, Jay H.[et al.] (Wiley, 2022)
Background and Aims: Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network ... -
A revised electronic version of RUCAM for the diagnosis of DILI.
Hayashi, PH; Lucena-González, María Isabel; Fontana, RJ; Bjornsson, ES; Aithal, GP; Barnhart, H; González-Jiménez, Andrés; Yang, Q; Gu, J; Andrade-Bellido, Raúl Jesús; Hoofnagle, JH[et al.] (LIPPINCOTT WILLIAMS & WILKINS, 2022-07)
Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network (DILIN) and the Spanish ... -
Análisis de las propiedades farmacológicas, los factores del huésped y su interacción en el desarrollo de hepatotoxicidad asociada a fármacos
(UMA Editorial, 2017)INTRODUCTION Drug-induced liver injury is an important concern in public health. In addition, it is one of the most common adverse events that cause lack of drug approval, drug withdrawals, and post-marketing regulatory ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
Stephens, Camilla; Robles-Díaz, María Mercedes; Medina-Cáliz, Inmaculada; García-Cortés, Miren; Ortega-Alonso, Aida; Sanabria-Cabrera, Judith Adriana; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Slim, Mahmoud; Jiménez-Pérez, Miguel; González-Grande, Rocío; Fernández, M. Carmen; Casado, Marta; Soriano, German; Roman, Eva; Hallal, Hacibe; Romero-Gomez, Manuel; Castiella, Agustin; Conde, Isabel; Prieto, Martin; Moreno-Planas, José María; Giraldez, Alvaro; Moreno-Sanfiel, J Miguel; Kaplowitz, Neil; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (Elsevier, 2021-02-01)
Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine learning approach
González-Jiménez, Andrés; Suzuki, Ayako; Chen, Minjun; Ashby, Kristin; Alvarez-Alvarez, Ismael; Andrade-Bellido, Raúl Jesús; Lucena-González, María Isabel[et al.] (Springer, 2021-03-05)
Drug-induced liver injury (DILI) presentation varies biochemically and histologically. Certain drugs present quite consistent injury patterns, i.e., DILI signatures. In contrast, others are manifested as broader types of ... -
Elevated bilirubin, alkaline phosphatase at onset, and drug metabolism are associated with prolonged recovery from DILI.
Ashby, Kristin; Zhuang, Wei; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Lucena, M. Isabel; Andrade-Bellido, Raúl Jesús; Aithal, Guruprasad P.; Suzuki, Ayako; Chen, Minjun[et al.] (Elsevier, 2021)
Background & aims: Although most drug-induced liver injury (DILI) cases resolve after the offending medication is discontinued, time to recovery varies among patients, with 6 -12% developing a chronic disease. Herein, we ... -
Hepatic safety of atypical antipsychotics: current evidence and future directions
Slim, Mahmoud; Medina-Cáliz, Inmaculada; González-Jiménez, Andrés; Cabello-Porras, María Rosario; Mayoral Cleries, Fermín; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (Springer, ADIS INT LTD, 2016-10)
The newer atypical antipsychotic agents (AAPs) represent an attractive therapeutic option for a wide range of psychotic disorders, including schizophrenia and bipolar mania, because of the reduced risk of disabling ... -
Herbal and dietary supplement-induced liver injuries in the spanish DILI registry
Medina-Cáliz, Inmaculada; García-Cortés, Miren; González-Jiménez, Andrés; Cabello-Porras, María Rosario; Robles-Díaz, María Mercedes; Sanabria-Cabrera, Judith Adriana; Sanjuan-Jimenez, Rocio; Ortega-Alonso, Aida; García-Muñoz, Beatriz; Moreno, Inmaculada; Jiménez-Pérez, Miguel; Fernández, M. Carmen; Ginés, Pere; Prieto, Martin; Conde, Isabel; Hallal, Hacibe; Soriano, German; Roman, Eva; Castiella, Agustin; Blanco-Reina, Encarnación; Montes, Maria R; Quiros-Cano, Marta; Martín-Reyes, Flores; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (Elsevier, 2018-01)
There have been increasing reports of liver injury associated with use of herbal and dietary supplements.We collected and analyzed data on demographic and clinical features, along with biochemical parameters, of 32 patients ... -
Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug-Induced Liver Injury in the Spanish DILI Registry
Sanabria-Cabrera, Judith Adriana; Sanjuan-Jimenez, Rocio; Clavijo-Frutos, Encarnación; Medina-Cáliz, Inmaculada; González-Jiménez, Andrés; García-Cortés, Miren; Ortega-Alonso, Aida; Jiménez-Pérez, Miguel; González-Grande, Rocío; Stephens, Camilla; Robles-Díaz, María Mercedes; Lucena-González, María Isabel; Andrade-Bellido, Raúl Jesús[et al.] (2020)
Background and Aims: Drug-induced liver injury (DILI) presents with a wide phenotypic spectrum requiring an extensive differential diagnosis. Hepatitis E virus (HEV) is not systematically ruled out during acute hepatitis ... -
Lansoprazole Increases Inorganic Pyrophosphate in Patients with Pseudoxanthoma Elasticum: A Double-Blind, Randomized, Placebo-Controlled Crossover Trial
Murcia Casas, Belén; Carrillo Linares, Juan Luis; Baquero Aranda, Isabel; Rioja Villodres, José; Merino Bohórquez, Vicente; González-Jiménez, Andrés; Rico Corral, Miguel Ángel; Bosch, Ricardo; Sánchez Chaparro, Miguel ángel; García-Fernández, María Dolores; Valdivielso-Felices, Pedro[et al.] (MDPI, 2023-03-03)
Pseudoxanthoma elasticum (PXE) is characterized by low levels of inorganic pyrophosphate (PPi) and a high activity of tissue-nonspecific alkaline phosphatase (TNAP). Lansoprazole is a partial inhibitor of TNAP. The aim was ... -
Multi-Omics Approach Reveals Prebiotic and Potential Antioxidant Effects of Essential Oils from the Mediterranean Diet on Cardiometabolic Disorder Using Humanized Gnotobiotic Mice.
Sánchez-Quintero, María José; Delgado, Josué; Martín-Chaves, Laura; Medina-Vera, Dina; Murri, Mora; Becerra-Muñoz, Víctor Manuel; Estévez, Mario; Crespo-Leiro, María G.; Paz López, Guillermo; González-Jiménez, Andrés; García-Ranea, Juan Antonio; Queipo-Ortuño, María Isabel; Plaza-Andrades, Isaac; Rodríguez Capitán, Jorge; Pavón-Morón, Francisco Javier; Jiménez-Navarro, Manuel Francisco[et al.] (MDPI, 2023-08-20)
Essential oils sourced from herbs commonly used in the Mediterranean diet have demonstrated advantageous attributes as nutraceuticals and prebiotics within a model of severe cardiometabolic disorder. The primary objective ...