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Listar por autor "Lhamyani, Said"
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Adipogenic Impairment of Adipose Tissue-Derived Mesenchymal Stem Cells in Subjects With Metabolic Syndrome: Possible Protective Role of FGF2
Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Lhamyani, Said; Clemente-Postigo, María Mercedes; Alcaide Torres, Juan; Bernal-López, María Rosa; El-Bekay, Rajaa; Tinahones-Madueño, Francisco José[et al.] (Endocrine Society, 2017)Context: The decreased expansion capacity of adipose tissue plays a crucial role in the onset of disorders associated with metabolic syndrome. Objetive: The aim of this study was to examine the state of adipose tissue-derived ... -
Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia.
Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Lhamyani, Said; Salas-Millán, Manuel Julián; Gentile, Adriana Mariel; Romero-Zerbo, Silvana Yanina; Zayed, Hatem; Valderrama-Marcos, José Francisco; Tinahones-Madueño, Francisco José; El-Bekay, Rajaa[et al.] (Wiley, 2017)Adipose tissue‐derived multipotent mesenchymal cells (ASCs) participate in the information ofblood vessels under hypoxic conditions. It is probable that the susceptibility of ASCs to theinfluence of age and ageing‐associated ... -
Metabolic endotoxemia promotes adipose dysfunction and inflammation in human obesity
Clemente-Postigo, María Mercedes; Oliva Olivera, Wilfredo; Coín-Aragüez, Leticia I.; Ramos-Molina, Bruno; Giráldez-Pérez, Rosa María; Lhamyani, Said; Alcaide Torres, Juan; Pérez-Martínez, Pablo; El Bekay Rizky, Rajaa; Cardona-Díaz, Fernando; Tinahones-Madueño, Francisco José[et al.] (American Physiological Society, 2019)Impaired adipose tissue (AT) lipid handling and inflammation is associated with obesity-related metabolic diseases. Circulating lipopolysaccharides (LPSs) from gut microbiota (metabolic endotoxemia), proposed as a triggering ... -
Los microARNs angiogénicos de grasa tímica humana como fuente complementaria de angiogénesis y regeneración de tejidos isquémicos en cirugía coronaria
Gentile, Adriana Mariel; Lhamyani, Said; Salas, Julián; Olveira, Gabriel; El Bekay Rizky, Rajaa (2021-10-28)Introducción: Las enfermedades cardiovasculares crónicas representan un importante problema de salud. La cirugía de revascularización coronaria es la primera opción de tratamiento. Pero hay un 12% de pacientes que no están ... -
miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes.
Gentile, Adriana Mariel; Lhamyani, Said; Coín-Aragüez, Leticia I.; Clemente-Postigo, María Mercedes; Oliva Olivera, Wilfredo; Romero-Zerbo, Silvana Yanina; García Serrano, Sara; García-Escobar, Eva; Zayed, Hatem; Doblado, Esther; Bermúdez Silva, Francisco Javier; Murri, Mora; Tinahones-Madueño, Francisco José; El-Bekay, Rajaa[et al.] (Wiley, 2019)Objective: This study aimed to analyze the potential association of different microRNA (miRNA) moleculeswith both type 2 diabetes (T2D) and obesity and determine their target genes.Methods: Quantitative PCR was used to ... -
Papel de miR-21 en la activación del browning. Una posible estrategia para combatir la obesidad y la resistencia a la insulina.
Lhamyani, Said (UMA Editorial, 2017-10-05)Objetivos del estudio: La regulación de la expansión del tejido adiposo (TA) está relacionada con el desarrollo de la obesidad y las comorbidades asociadas a ella, como la resistencia a la insulina. Es conocido que el ... -
RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
Gentile, Adriana Mariel; Lhamyani, Said; Coín-Aragüez, Leticia I.; Oliva Olivera, Wilfredo; Zayed, Hatem; Vega-Rioja, Antonio; Monteseirin, Javier; Romero-Zerbo, Silvana Yanina; Tinahones-Madueño, Francisco José; Bermúdez Silva, Francisco Javier; El-Bekay, Rajaa[et al.] (Public Library of Science, 2016)Real-time or quantitative PCR (qPCR) is a useful technique that requires reliable reference genes for data normalization in gene expression analysis. Adipogenesis is among the biological processes suitable for this technique. ... -
The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice
Bermúdez Silva, Francisco Javier; Romero-Zerbo, Silvana Yanina; Haissaguerre, Magalie; Ruz-Maldonado, Inmaculada; Lhamyani, Said; El-Bekay, Rajaa; Tabarin, Antoine; Marsicano, Giovanni; Cota, Daniela[et al.] (The Company of Biologists, 2016)The endocannabinoid system (ECS) is an intercellular signalling mechanism that is present in the islets of Langerhans and plays a role in the modulation of insulin secretion and expansion of the β-cell mass. The downstream ...