Among all the factors that can contribute to the onset of psychopathological disorders, stress is the main environmental factor. The hippocampus is one of the most sensitive regions to the harmful effects of stress, in ...

We have examined the effect of an acute stress in the proteomic profile of hypothalamus. For this purpose, to extract information from proteomic profiles (1 and 24 hours post-acute stress) a Quadrupole-Orbitrap mass ...

Introduction: Chronic stress is the main environmental factor in the aetiology of depression and it is known that this type of stress may cause alterations in brain regions such as the hippocampus. Nevertheless, changes ...

Depression is a concerning public health threat highly associated with stress. Stress increases brain immune alterations, namely in microglia, which can affect neuron physiology, like neurogenesis, causing a depressive-like ...

Microglial cells are an important glial population known to be involved in several biological processes such as stress response. These cells engage an activated state following a stress insult that may lead to nervous ...

Introduction: It is well known that early life adversities could a"ect brain development and increase the vulnerability to stress-related disorders later in adulthood. Nevertheless, the neurobiological mechanisms underlying ...

Stress is the main environmental cause for depression, known to cause brain immune alterations. As major brain immune cells, microglia undergo transcriptional and, consequently, morphological changes that result in ...