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Listar por autor "Melguizo, Consolación"
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Electrospun nanofibers: recent applications in drug delivery and cancer therapy
Contreras-Cáceres, Rafael; Cabeza, Laura; Perazzoli, Gloria; Díaz-Morilla, Amelia; López-Romero, Juan Manuel; Melguizo, Consolación; Prados, Jose[et al.] (MDPI, 2019-04)Polymeric nanofibers (NFs) have been extensively reported as a biocompatible scaffold to be specifically applied in several researching fields, including biomedical applications. The principal researching lines cover the ... -
Magnetically active pNIPAM nanosystems as temperature-sensitive biocompatible structures for controlled drug delivery
García-Pinel, Beatriz; Ortega Rodríguez, Alicia; Porras Alcalá, Cristina; Cabeza, Laura; Contreras-Cáceres, Rafael; Ortiz, Raúl; Díaz-Morilla, Amelia; Moscoso, Ana; Sarabia-García, Francisco Ramón; Prados, Jose; López-Romero, Juan Manuel; Melguizo, Consolación[et al.] (Taylor and Francis, 2020-04-19)Here, temperature-sensitive hybrid poly(N-isopropylacrylamide) (pNIPAM) nanosystems with magnetic response are synthesised and investigated for controlled release of 5-fluorouracil (5FU) and oxaliplatin (OXA). Initially, ... -
Synthesis of New Analogues of the Bengamides to encapsulate in magnetic nanoparticles
Ortega Rodríguez, Alicia; Porras Alcalá, Cristina; Contreras-Cáceres, Rafael; López-Romero, Juan Manuel; Melguizo, Consolación; Prados, José Carlos[et al.] (2019-05-15)The development and identification of new antitumoral has become a research area of great interest and maximum priority due to secondary effects of current antitumoral and the appearance of tumours resistant to these agents. ... -
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria
Porras Alcalá, Cristina; Moya-Utrera, Federico; García-Castro, Miguel; Sánchez-Ruiz, Antonio; López-Romero, Juan Manuel; Pino-González, María Soledad; Díaz-Morilla, Amelia; Kitamura, Seiya; W. Wolan, Dennis; Prados, Jose; Melguizo, Consolación; Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón[et al.] (IOAP-MPDI, 2022-05-31)The bengamides comprise an interesting family of natural products isolated from sponges belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled with their unique mechanism of action and ... -
Thermorresponsive magnetic nanoparticles as target drug delivery for cancer treatment
Ortega Rodríguez, Alicia; Porras Alcalá, Cristina; Contreras-Cáceres, Rafael; López-Romero, Juan Manuel; Melguizo, Consolación; Prados, José Carlos[et al.] (2019-05-15)In this research, temperature sensitive microgels with magnetic core for controlled release of 5-fluoruracil was synthesized. Magnetic nanoparticles (Fe3O4) were prepared by coprecipitation method and the surface was ...