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Listar por autor "Fernández-Trujillo, M. Alejandra"
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Antiviral activity of mx proteins from gilthead seabream (sparus aurata) against lymphocystis disease virus (LCDV).
Fernández-Trujillo, M. Alejandra; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (ELSEVIER, 2013)Gilthead seabream (Sparus aurata), one of the most important fish species in the Mediterranean Aquaculture displays a high natural resistance to viral diseases. Until now, the main viral disease affecting gilthead seabream ... -
Development of in vitro systems to study IFN signalling in gilthead seabream (Sparus aurata)
González-Mariscal, J.A.; Fernández-Trujillo, M. Alejandra; Méndez, T.; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-12-11)Type I interferon (IFN I) triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. In contrats, type II IFN (IFN II) is generally accepted to be ... -
Differential induction of the gilthead seabream Mx1, Mx2 and Mx3 promoters by IPNV and VHSV
González-Mariscal, J.A.; Fernández-Trujillo, M. Alejandra; Méndez, T.; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)Type I interferon (IFN I) system triggers specific signalling pathways leading to the activation of the innate immune defence of vertebrates against viral infections. The complex expression regulation of Interferon Stimulated ... -
Las dos proteínas Mx de lubina (Dicentrarchus labrax) responden de forma diferente a la infección por VNNV
Novel, Patricia; Fernández-Trujillo, M. Alejandra; Manchado, Manuel; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia (2013-10-01)Las proteínas Mx son elementos clave en el estado antiviral desencadenado por el interferón tipo I en respuesta a las infecciones virales. En este trabajo se han identificado dos genes Mx en lubina (Dicentrarchus labrax), ... -
Gilthead seabream (Sparus aurata) Mx proteins show positive and negative synergy in their antiviral activity
Fernández-Trujillo, M. Alejandra; García-Rosado, Esther; Alonso-Sánchez, María del Carmen; Borrego-García, Juan José; Álvarez-Herrero, María del Carmen; Béjar-Alvarado, Julia[et al.] (2014-10-07)Due to their direct antiviral activity, Mx proteins play a main role in the response mediated by the type I interferon against viral infections. The study of the farmed fish gilthead seabream Mx genes is specially interesting, ... -
Inducción de las proteínas Mx por interferón tipo I en células de dorada y de trucha
Béjar-Alvarado, Julia; Núñez, Encarnación; Fernández-Trujillo, M. Alejandra; Álvarez-Herrero, María del Carmen (2015-10-26)Characterizing the innate immune system defence mechanisms is essential to develop preventive measures against viral infections in aquaculture. In this study, the intra-specific differential response of Mx proteins to type ...