Listar por autor "Gémez-Mata, Juan"
Mostrando ítems 1-20 de 22
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Actividad antagonista de aislados del Virus de la Septicemia Hemorrágica Viral (VHSV) frente al sistema del interferón tipo I de lenguado senegalés
Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther
; Alonso-Sánchez, María del Carmen; Béjar-Alvarado, Julia (2017-10-11)
Senegalese sole (Solea senegalensis) is susceptible to marine Viral Haemorrhagic Septicaemia Virus (VHSV) isolates, but it is not affected by freshwater VHSV isolates. In addition, the sole type I interferon (IFN I) response ... -
Análisis de la expresión de inmunogenes en doradas vacunadas en respuesta a la infección por LCDV-Sa
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Castro-López, María Dolores; Borrego-García, Juan José (2021)
El objetivo del presente estudio ha sido evaluar la respuesta inmune frente a la infección por Lymphocystis Disease Virus 3 (LCDV-Sa) en ejemplares de dorada (Sparus aurata) vacunados con un plásmido que codifica la proteína ... -
Differential immunogene expression profile of European sea bass (Dicentrarchus labrax, L.) in response to highly and low virulent NN
Moreno, Patricia; Gémez-Mata, Juan; García-Rosado, Esther; Béjar-Alvarado, Julia; Labella Vera, Alejandro Manuel; Souto, Sandra; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2020)
European sea bass is highly susceptible to the nervous necrosis virus, RGNNV genotype, whereas natural outbreaks caused by the SJNNV genotype have not been recorded. The onset and severity of an infectious disease depend ... -
Estudio in vitro de la actividad antagonista de aislados del virus de la septicemia hemorrágica viral (VHSV) de distinto origen sobre el sistema del IFN tipo I
Gémez-Mata, Juan; Álvarez-Torres, Daniel; Alonso-Sánchez, María del Carmen; García-Rosado, Esther; Béjar-Alvarado, Julia (2018-11-09)
El lenguado senegalés (Solea senegalensis) es susceptible a aislados marinos del virus de la septicemia hemorrágica viral (VHSV); sin embargo, los VHSV patógenos para especies de agua dulce no son virulentos para especies ... -
European sea bass RTP3 genes: genomic characterization and transcription analyses.
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (2023)
Introduction: Fish RTP3, belonging to receptor-transporting protein (RTP) family, has been described as an interferon-α (IFN-α)-responsive gene. However, little information is available about fish rtp3 gene structure and ... -
Evaluación de la respuesta inmune en doradas tras la administración de una vacuna inactivada frente a betanodavirus
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno, Patricia; Borrego-García, Juan José; García-Rosado, Esther; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
El virus de la necrosis nerviosa (VNN), género Betanodavirus, familia Nodaviridae, es el agente etiológico de la necrosis nerviosa viral, enfermedad que afecta a peces cultivados en todo el mundo. Existen cuatro especies ... -
Evaluación de la respuesta inmune en lenguado senegalés conferida por una vacuna inactivada frente a Betanodavirus
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; López-Vázquez, Carmen; Olveira, José G.; Bandín Matos, Isabel; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel[et al.] (2022)
La necrosis nerviosa viral es una enfermedad que afecta a peces cultivados en todo el mundo. Su agente etiológico es el virus de la necrosis nerviosa, género Betanodavirus, familia Nodaviridae, que presenta un genoma ... -
Evaluation of immune response after LCDV-Sa infection in DNA-vaccinated gilthead seabream
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2021)
The immune-related gene expression in vaccinated gilthead seabream after Lymphocystis Disease Virus 3 (LCDV-Sa) infection was analysed by using an OpenArray based on TaqMan qPCR. The DNA vaccine used in this study encodes ... -
Evaluation of the immune response in betanodavirus-vaccinated gilthead seabream.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
An inactivated vaccine has been developed using a RGNNV/SJNNV reassortant strain isolated from Senegalese sole, which confers moderate protection against the homologous viral strain in sole juveniles. The aim of this study ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes
Moreno-García, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)
Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Genomic characterization and transcription analysis of European sea bass (Dicentrarchus labrax) rtp3 genes.
Moreno, Patricia; Gémez-Mata, Juan; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Elsevier, 2023-10-23)
Fish RTP3, belonging to the receptor-transporting protein family, display several functions, including a putative antiviral role as virus-responsive gene. In this work, we have identified and characterized two different ... -
Immune gene expression in gilthead seabream after nervous necrosis virus (NNV) challenge
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2022-09)
Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus (NNV), genus Betanodavirus, family Nodaviridae. NNV are small and non-enveloped viruses with ... -
Immune response of DNA vaccinated-gilthead seabream against LCDV-Sa infection: relevance of the inflammatory process.
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Castro-López, María Dolores; Borrego-García, Juan José; Labella Vera, Alejandro Manuel (2023)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. Recently, we have developed a DNA-vaccine based on the major capsid protein of the Lymphocystis ... -
Immune response of gilthead seabream infected with wild and mutant nervous necrosis virus reassortants.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2023)
Viral nervous necrosis (VNN) is a disease that affects farmed fish worldwide. Its etiologic agent is the nervous necrosis virus currently classified into 4 species: SJNNV, RGNNV, TPNNV and BFNNV. In Southern Europe, ... -
Immune response of Senegalese sole and gilthead seabream after vaccination with an inactivated vaccine against betanodavirus.
Gémez-Mata, Juan; Leiva-Rebollo, Rocío; Moreno-García, Patricia; Bandín Matos, Isabel; Borrego-García, Juan José; Labella Vera, Alejandro Manuel; Castro-López, María Dolores[et al.] (2024)
Nervous necrosis virus (NNV) (genus Betanodavirus, family Nodaviridae) is the etiologic agent of viral encephalopathy and retinopathy (VER). This virus is classified into four species: SJNNV, RGNNV, TPNNV and BFNNV. In ... -
Immune response of vaccinated juvenile gilthead seabream (Sparus aurata) after LCDV-Sa infection
Leiva-Rebollo, Rocío; Gémez-Mata, Juan; Borrego-García, Juan José; Castro-López, María Dolores; Labella Vera, Alejandro Manuel (2022-09)
Lymphocystis disease is one of the main viral pathologies affecting cultured gilthead seabream in the Mediterranean area. In our group, a DNA-vaccine has been developed based on the major capsid protein (MCP) of the ... -
Immunogene expression analysis in betanodavirus infected-Senegalese sole using an OpenArray® platform.
Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Bandín Matos, Isabel; Borrego-García, Juan José; García-Rosado, Esther (ELSEVIER, 2021-03-30)
The transcriptomic response of Senegalese sole (Solea senegalensis) triggered by two betanodaviruses with different virulence to that fish species has been assessed using an OpenArray® platform based on TaqMan™ quantitative ... -
Juvenile gilthead sea bream immune response against RGNNV or RGNNV/SJNNV infections
Gémez-Mata, Juan; Moreno Garcia, Patricia; Álvarez-Torres, Daniel; García-Rosado, Esther; Béjar-Alvarado, Julia; Alonso-Sánchez, María del Carmen[et al.] (Sociedad Española de Virología, 2024-09-02)
Viral nervous necrosis is one of the main threats for the aquaculture. It is caused by the nervous necrosis virus (NNV), with a genome composed of two positive-sense, ssRNA segments: RNA1, encoding the viral polymerase; ... -
Senegalese sole immune response against betanodavirus recombinants harboring modifications in the 3' terminal region of the RNA1
Gémez-Mata, Juan; Labella Vera, Alejandro Manuel; Souto, Sandra; Bandín Matos, Isabel; Borrego-García, Juan José; García-Rosado, Esther[et al.] (2021-09)
The nervous necrosis virus (NNV) is the etiological agent of the viral nervous necrosis (VNN), a disease affecting a high number of fish species worldwide. NNV genome is composed of two segments RNA1 and RNA2, encoding the ... -
Shewanella putrefaciens Pdp11 extracts promote European sea bass resistance against RGNNV infection.
Moreno-García, Patricia; Álvarez-Torres, Daniel; Gémez-Mata, Juan; Balebona-Accino, María del Carmen; Domínguez-Maqueda, Marta; Cerezo-Domínguez, Ana Isabel; Moriñigo-Gutiérrez, Miguel Ángel; Béjar-Alvarado, Julia; García-Rosado, Esther; Alonso-Sánchez, María del Carmen[et al.] (2024)
The viral nervous necrosis (VNN) is a neurotropic disease affecting different fish species, resulting in high mortality rates. The causal agent is the nervous necrosis virus (NNV), belonging to the Betanodavirus genus, ...